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Interferon Regulatory Factor 4

Known as: LSIRF protein, human, IRF-4, hLSIRF protein, human 
Interferon regulatory factor 4 (451 aa, ~52 kDa) is encoded by the human IRF4 gene. This protein is involved in the mediation of both T-cell… 
National Institutes of Health

Related topics

Related topics

11 relations
Cell Differentiation processCell NucleusDNA-Binding ProteinsGenes, Regulator

Broader (2)

IRF4 wt Alleleinterferon regulatory factor-4

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Enhancement of pomalidomide anti-tumor response with ACY-241, a selective HDAC6 inhibitor
Thalidomide-based Immunomodulatory Drugs (IMiDs®), including lenalidomide and pomalidomide, are effective therapeutics for… 
Highly Cited
2012
Highly Cited
2012
Direct interaction of PU.1 with oncogenic transcription factors reduces its serine phosphorylation and promoter binding
2012
2012
An in vivo proteomic study of the interaction between Salmonella Typhimurium and porcine ileum mucosa.
Highly Cited
2010
Highly Cited
2010
Conversion of Th2 memory cells into Foxp3+ regulatory T cells suppressing Th2-mediated allergic asthma
Genetic and epigenetic programming of T helper (Th) cell subsets during their polarization from naive Th cells establishes long… 
2009
2009
NF-κB activity marks cells engaged in receptor editing
Because of the extreme diversity in immunoglobulin genes, tolerance mechanisms are necessary to ensure that B cells do not… 
2008
2008
Regulation of Telomerase Activity by Interferon Regulatory Factors 4 and 8 in Immune Cells
ABSTRACT Telomerase activity is downregulated in somatic cells but is upregulated during the activation of cells of the immune… 
2005
2005
Tracing the Pre-B to Immature B Cell Transition in Human Leukemia Cells Reveals a Coordinated Sequence of Primary and Secondary IGK Gene Rearrangement, IGK Deletion, and IGL Gene Rearrangement1
The BCR-ABL1 kinase expressed in acute lymphoblastic leukemia (ALL) drives malignant transformation of pre-B cells and prevents… 
2004
2004
Enhanced TCR-induced Apoptosis in Interferon Regulatory Factor 4–deficient CD4+ Th Cells
Transcription factors of the interferon regulatory factor (IRF) family contribute to the regulation of cell proliferation and… 
2001
2001
Interferon Regulatory Factor 4 Contributes to Transformation of v-Rel-Expressing Fibroblasts
ABSTRACT The avian homologue of the interferon regulatory factor 4 (IRF-4) and a novel splice variant lacking exon 6, IRF-4ΔE6… 
2000
2000
Activation and regulation of interferon regulatory factor 4 in HTLV type 1-infected T lymphocytes.
The human T cell leukemia virus type 1 (HTLV-1) is the etiologic agent of adult T cell leukemia (ATL), an aggressive and fatal… 
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