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Interferon Regulatory Factor 4
Known as:
LSIRF protein, human
, IRF-4
, hLSIRF protein, human
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Interferon regulatory factor 4 (451 aa, ~52 kDa) is encoded by the human IRF4 gene. This protein is involved in the mediation of both T-cell…
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National Institutes of Health
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Related topics
Related topics
11 relations
Cell Differentiation process
Cell Nucleus
DNA-Binding Proteins
Genes, Regulator
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Broader (2)
IRF4 wt Allele
interferon regulatory factor-4
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Enhancement of pomalidomide anti-tumor response with ACY-241, a selective HDAC6 inhibitor
Brian J. North
,
Ingrid Almeciga-Pinto
,
D. Tamang
,
Min Yang
,
Simon S. Jones
,
S. Quayle
PLoS ONE
2017
Corpus ID: 13929984
Thalidomide-based Immunomodulatory Drugs (IMiDs®), including lenalidomide and pomalidomide, are effective therapeutics for…
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Highly Cited
2012
Highly Cited
2012
Direct interaction of PU.1 with oncogenic transcription factors reduces its serine phosphorylation and promoter binding
A. Seshire
,
T. Rößiger
,
M. Frech
,
S. Beez
,
H. Hagemeyer
,
E. Puccetti
Leukemia
2012
Corpus ID: 4299747
2012
2012
An in vivo proteomic study of the interaction between Salmonella Typhimurium and porcine ileum mucosa.
Melania Collado-Romero
,
R. P. Martins
,
+4 authors
J. Garrido
Journal of Proteomics
2012
Corpus ID: 7357159
Highly Cited
2010
Highly Cited
2010
Conversion of Th2 memory cells into Foxp3+ regulatory T cells suppressing Th2-mediated allergic asthma
Byung-Seok Kim
,
Il-Kyu Kim
,
+7 authors
C. Kang
Proceedings of the National Academy of Sciences…
2010
Corpus ID: 23974438
Genetic and epigenetic programming of T helper (Th) cell subsets during their polarization from naive Th cells establishes long…
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2009
2009
NF-κB activity marks cells engaged in receptor editing
Emily J Cadera
,
F. Wan
,
Rupesh H. Amin
,
H. Nolla
,
M. Lenardo
,
Mark Schlissel
Journal of Experimental Medicine
2009
Corpus ID: 7180970
Because of the extreme diversity in immunoglobulin genes, tolerance mechanisms are necessary to ensure that B cells do not…
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2008
2008
Regulation of Telomerase Activity by Interferon Regulatory Factors 4 and 8 in Immune Cells
R. Hrdličková
,
J. Nehyba
,
H. Bose
Molecular and Cellular Biology
2008
Corpus ID: 35225751
ABSTRACT Telomerase activity is downregulated in somatic cells but is upregulated during the activation of cells of the immune…
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2005
2005
Tracing the Pre-B to Immature B Cell Transition in Human Leukemia Cells Reveals a Coordinated Sequence of Primary and Secondary IGK Gene Rearrangement, IGK Deletion, and IGL Gene Rearrangement1
F. Klein
,
N. Feldhahn
,
+5 authors
M. Müschen
Journal of Immunology
2005
Corpus ID: 15753722
The BCR-ABL1 kinase expressed in acute lymphoblastic leukemia (ALL) drives malignant transformation of pre-B cells and prevents…
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2004
2004
Enhanced TCR-induced Apoptosis in Interferon Regulatory Factor 4–deficient CD4+ Th Cells
M. Lohoff
,
H. Mittrücker
,
+6 authors
T. Mak
Journal of Experimental Medicine
2004
Corpus ID: 9693784
Transcription factors of the interferon regulatory factor (IRF) family contribute to the regulation of cell proliferation and…
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2001
2001
Interferon Regulatory Factor 4 Contributes to Transformation of v-Rel-Expressing Fibroblasts
R. Hrdličková
,
J. Nehyba
,
H. Bose
Molecular and Cellular Biology
2001
Corpus ID: 14804570
ABSTRACT The avian homologue of the interferon regulatory factor 4 (IRF-4) and a novel splice variant lacking exon 6, IRF-4ΔE6…
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2000
2000
Activation and regulation of interferon regulatory factor 4 in HTLV type 1-infected T lymphocytes.
S. Sharma
,
Y. Mamane
,
+4 authors
J. Hiscott
AIDS Research and Human Retroviruses
2000
Corpus ID: 20910161
The human T cell leukemia virus type 1 (HTLV-1) is the etiologic agent of adult T cell leukemia (ATL), an aggressive and fatal…
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