Interferon Regulatory Factor 4

Known as: LSIRF protein, human, IRF-4, hLSIRF protein, human 
Interferon regulatory factor 4 (451 aa, ~52 kDa) is encoded by the human IRF4 gene. This protein is involved in the mediation of both T-cell… (More)
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
Upon infection, CD8(+) T cells undergo a stepwise process of early activation, expansion, and differentiation into effector cells… (More)
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Highly Cited
2010
Highly Cited
2010
Interferon-regulatory factor 4 (IRF4) is essential for the development of T helper 2 (Th2) and Th17 cells. Herein, we report that… (More)
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Highly Cited
2009
Highly Cited
2009
In the course of infection or autoimmunity, particular transcription factors orchestrate the differentiation of TH1, TH2 or TH17… (More)
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Highly Cited
2007
Highly Cited
2007
Interferon-regulatory factor 4 (IRF4) is essential for the development of T helper type 2 cells. Here we show that IRF4 is also… (More)
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Highly Cited
2006
Highly Cited
2006
Molecular mechanisms underlying the coordination of isotype switching with plasma cell differentiation are poorly understood. We… (More)
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Highly Cited
2005
Highly Cited
2005
Dendritic cells (DCs) are bone marrow (BM)-derived APCs central to both innate and adaptive immunity. DCs are a heterogeneous… (More)
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Highly Cited
2004
Highly Cited
2004
IFN regulatory factors (IRFs) are a family of transcription factors that play an essential role in the homeostasis and function… (More)
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Highly Cited
2002
Highly Cited
2002
Proteins of the nuclear factor of activated T cells (NFAT) family of transcription factors are critical for lymphocyte activation… (More)
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Highly Cited
2002
Highly Cited
2002
Certain IFN regulatory factor (IRF) transcription factors indirectly influence T helper (Th) cell differentiation by regulating… (More)
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Highly Cited
2000
Highly Cited
2000
In lymphocytes, the Rel transcription factor is essential in establishing a pattern of gene expression that promotes cell… (More)
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