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Insulin-resistant diabetes mellitus

Known as: diabetes resistant insulin, Insulin resistant diabetes mellitus, Insulin-resistant diabetes 
A type of diabetes mellitus related not to lack of insulin but rather to lack of response to insulin on the part of the target tissues of insulin… 
National Institutes of Health

Related topics

Related topics

9 relations
Alstrom SyndromeFamilial Partial Lipodystrophy, Type 1Familial Partial Lipodystrophy, Type 3LIPODYSTROPHY, FAMILIAL PARTIAL, TYPE 4

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2013
Review
2013
Atypical antipsychotics in the treatment of children and adolescents with pervasive developmental disorders
Autism and related pervasive developmental disorders (PDD) are characterized by impairments in social interaction and… 
Review
2010
Review
2010
PPAR/RXR Regulation of Fatty Acid Metabolism and Fatty Acid ω-Hydroxylase (CYP4) Isozymes: Implications for Prevention of Lipotoxicity in Fatty Liver Disease
Fatty liver disease is a common lipid metabolism disorder influenced by the combination of individual genetic makeup, drug… 
Highly Cited
2003
Highly Cited
2003
Overexpression of Plasma Membrane-associated Sialidase Attenuates Insulin Signaling in Transgenic Mice*
Plasma membrane-associated sialidase is a key enzyme for ganglioside hydrolysis, thereby playing crucial roles in regulation of… 
Review
2000
Review
2000
Lipoatrophy Revisited
Highly Cited
1999
Highly Cited
1999
Enhanced insulin-stimulated activation of phosphatidylinositol 3-kinase in the liver of high-fat-fed rats.
Insulin receptor substrate (IRS)-1 and IRS-2, which mediate phosphatidylinositol (PI) 3-kinase activation, play essential roles… 
Highly Cited
1999
Highly Cited
1999
Triglyceride-induced diabetes associated with familial lipoprotein lipase deficiency.
Raised plasma triglycerides (TGs) and nonesterified fatty acid (NEFA) concentrations are thought to play a role in the… 
Highly Cited
1997
Highly Cited
1997
Troglitazone action is independent of adipose tissue.
We have investigated the antidiabetic action of troglitazone in aP2/DTA mice, whose white and brown fat was virtually eliminated… 
Review
1995
Review
1995
Pharmacology of receptors for calcitonin gene-related peptide and amylin.
Highly Cited
1991
Highly Cited
1991
Genetic basis of endocrine disease. 1. Molecular genetics of insulin resistant diabetes mellitus.
GENETIC factors are an important determinant of whether an individual will develop noninsulindependent diabetes mellitus (NIDDM… 
Highly Cited
1989
Highly Cited
1989
Human diabetes associated with a deletion of the tyrosine kinase domain of the insulin receptor.
The insulin receptor has an intrinsic tyrosine kinase activity that is essential for signal transduction. A mutant insulin… 
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