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Insulin Resistance

Known as: Insulin Resistance [Disease/Finding], Resistance, Insulin 
Diminished effectiveness of INSULIN in lowering blood sugar levels: requiring the use of 200 units or more of insulin per day to prevent… 
National Institutes of Health

Related topics

Related topics

17 relations
ANDIBULAR HYPOPLASIA, DEAFNESS, PROGEROID FEATURES, AND LIPODYSTROPHY SYNDROMEDiabetes MellitusDonohue SyndromeInsulin Resistance Measurement
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Narrower (2)

Diabetes Mellitus, Insulin-Resistant, with Acanthosis NigricansHAIR-AN syndrome

Broader (2)

Drug resistanceinsulin sensitivity/resistance

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2007
Highly Cited
2007
Metabolic Endotoxemia Initiates Obesity and Insulin Resistance
Diabetes and obesity are two metabolic diseases characterized by insulin resistance and a low-grade inflammation. Seeking an… 
Review
2006
Review
2006
Mechanisms linking obesity to insulin resistance and type 2 diabetes
Obesity is associated with an increased risk of developing insulin resistance and type 2 diabetes. In obese individuals, adipose… 
Review
2006
Review
2006
Inflammation and insulin resistance.
Over a hundred years ago, high doses of salicylates were shown to lower glucose levels in diabetic patients. This should have… 
Highly Cited
2004
Highly Cited
2004
Homeostasis model assessment: insulin resistance and β-cell function from fasting plasma glucose and insulin concentrations in man
SummaryThe steady-state basal plasma glucose and insulin concentrations are determined by their interaction in a feedback loop. A… 
Highly Cited
2003
Highly Cited
2003
Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance.
Insulin resistance arises from the inability of insulin to act normally in regulating nutrient metabolism in peripheral tissues… 
Highly Cited
2001
Highly Cited
2001
The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity
Adiponectin is an adipocyte-derived hormone. Recent genome-wide scans have mapped a susceptibility locus for type 2 diabetes and… 
Highly Cited
1995
Highly Cited
1995
Increased adipose tissue expression of tumor necrosis factor-alpha in human obesity and insulin resistance.
Obesity is frequently associated with insulin resistance and abnormal glucose homeostasis. Recent studies in animal models have… 
Highly Cited
1993
Highly Cited
1993
Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance.
Tumor necrosis factor-alpha (TNF-alpha) has been shown to have certain catabolic effects on fat cells and whole animals. An… 
Review
1991
Review
1991
Insulin Resistance: A Multifaceted Syndrome Responsible for NIDDM, Obesity, Hypertension, Dyslipidemia, and Atherosclerotic Cardiovascular Disease
Diabetes mellitus is commonly associated with systolic/diastolic hypertension, and a wealth of epidemiological data suggest that… 
Highly Cited
1988
Highly Cited
1988
Role of Insulin Resistance in Human Disease
Resistance to insulin-stimulated glucose uptake is present in the majority of patients with impaired glucose tolerance (IGT) or… 
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