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Insulin Resistance

Known as: Insulin Resistance [Disease/Finding], Resistance, Insulin 
Diminished effectiveness of INSULIN in lowering blood sugar levels: requiring the use of 200 units or more of insulin per day to prevent… 
National Institutes of Health

Related topics

Related topics

17 relations
ANDIBULAR HYPOPLASIA, DEAFNESS, PROGEROID FEATURES, AND LIPODYSTROPHY SYNDROMEDiabetes MellitusDonohue SyndromeInsulin Resistance Measurement

Narrower (2)

Diabetes Mellitus, Insulin-Resistant, with Acanthosis NigricansHAIR-AN syndrome

Broader (2)

Drug resistanceinsulin sensitivity/resistance

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2016
Highly Cited
2016
Mitochondrial Dynamics and Oxidative Stress Lipotoxicity in steatohepatitis occurs despite an increase in tricarboxylic acid cycle activity
Rainey E. Patterson,* Srilaxmi Kalavalapalli,* Caroline M. Williams, Manisha Nautiyal, Justin T. Mathew, Janie Martinez, Mary K… 
Review
2001
Review
2001
An overview of pathophysiology and treatment of insulin resistance.
Insulin resistance has emerged out as a concept linking diabetes mellitus and hypertension. Clinically it is characterized by… 
Highly Cited
2001
Highly Cited
2001
Mechanism of amelioration of insulin resistance by beta3-adrenoceptor agonist AJ-9677 in the KK-Ay/Ta diabetic obese mouse model.
The mechanism by which the specific beta3-adrenoceptor agonist AJ-9677 relieves insulin resistance in vivo was investigated by… 
Highly Cited
1988
Highly Cited
1988
Beta-cell deficiency, insulin resistance, or both?
Non-insulin-dependent diabetes (Type II, or maturity-onset diabetes) remains a popular topic in biomedical science because of its… 
Review
1984
Review
1984
Insulin is the mediator of feeding-related thermogenesis: insulin resistance and/or deficiency results in a thermogenic defect which contributes to the pathogenesis of obesity.
Obesity is characterized by insulin resistance which predisposes to the development of impaired glucose tolerance. It is… 
Highly Cited
1984
Highly Cited
1984
Tyrosine kinase activity of the insulin receptor of patients with type A extreme insulin resistance: studies with circulating mononuclear cells and cultured lymphocytes.
The syndrome of type A insulin resistance in nonobese women is characterized by hyperinsulinemia, resistance to exogenous insulin… 
Highly Cited
1982
Highly Cited
1982
Insulin resistance and diabetes due to a genetic defect in insulin receptors.
A 14-yr-old woman presented with fasting hyperglycemia (269 mg/dl), fasting hyperinsulinemia (45 microU/ml), acanthosis nigricans… 
Highly Cited
1981
Highly Cited
1981
Erythrocyte and Monocyte Insulin Binding in Man: A Comparative Analysis in Normal and Disease States
Blood cells have been widely used to evaluate the status of the insulin receptor in man. The insulin receptor of human monocytes… 
1979
1979
Accelerated Insulin Degradation: An Alternate Mechanism for Insulin Resistance
We have examined insulin and glucagon degrading activities of muscle and fat tissues in 11 subjects (4 lean controls, 3 insulin… 
Highly Cited
1979
Highly Cited
1979
Downregulation of Insulin Receptors in Obese Man
In an attempt to determine whether the decreased number of insulin's receptors in obesity is a result of downregulation of the…