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Feeding a high-fat diet (HFD) to rabbits results in increased blood pressure and renal sympathetic nerve activity (RSNA) and… Expand IGF-I is recognized as an insulin sensitizer at the liver and muscle, while recent evidence suggests that IGF-binding protein… Expand Nutrients are critical for optimal brain development and function. Although maintenance of adequate intake of all nutrients… Expand Insulin-like growth factor-I (IGF-I) has significant structural homology with proinsulin. IGF-I binds to insulin receptors… Expand Background/Aims: Insulin resistance is a well-known phenomenon in uremia. Resistin, a recently discovered insulin inhibitor… Expand Insulin resistance is defined as a failure of target organs to respond normally to the action of insulin. Insulin resistance… Expand BACKGROUND
Resistin is a newly discovered insulin inhibitor secreted by adipocytes. We explored the potential role of resistin in… Expand Estrogen-induced loss of estrogen receptor (ER) α expression limits estrogen responsiveness in many target cells. However… Expand In 1956 Prader and his associates described a syndrome of obesity, small stature, acromicria and oligophrenia, regularly preceded… Expand 1. The presence of a substance associated with human albumin that exerts anti-insulin activity on the isolated rat diaphragm has… Expand