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Inositol Polyphosphate 5-Phosphatases

Known as: Inositol Triphosphate 5 Phosphatase, Inositol Polyphosphate 5 Phosphatase, Inositol 5-Phosphatase 
Phosphoinositide phosphatases that catalyze the removal of the 5' phosphate from INOSITOL 1,4,5-TRISPHOSPHATE or myo-inositol 1,3,4,5… 
National Institutes of Health

Related topics

Related topics

10 relations

Broader (1)

Alkaline Phosphatase
INPP5J geneIn BloodProcess of secretionantagonists & inhibitors

Narrower (1)

inositol-1,4,5-trisphosphate 5-phosphatase

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2006
Review
2006
Regulation of phosphoinositide signaling by the inositol polyphosphate 5‐phosphatases
Phosphoinositide signaling molecules control cellular growth, proliferation and differentiation, intracellular vesicle… 
Highly Cited
2005
Highly Cited
2005
The SH2-domian-containing inositol 5-phosphatase (SHIP)-2 binds to c-Met directly via tyrosine residue 1356 and involves hepatocyte growth factor (HGF)-induced lamellipodium formation, cell…
Recently, evidence has been accumulating that inositol and phosphatidylinositol polyphosphate play important roles in a variety… 
2003
2003
Competitive fluorescence polarization assays for the detection of phosphoinositide kinase and phosphatase activity.
We describe the development and implementation of competitive fluorescence polarization (FP) based assays for determining… 
Highly Cited
2002
Highly Cited
2002
Nudix Hydrolases That Degrade Dinucleoside and Diphosphoinositol Polyphosphates Also Have 5-Phosphoribosyl 1-Pyrophosphate (PRPP) Pyrophosphatase Activity That Generates the Glycolytic Activator…
A total of 17 Nudix hydrolases were tested for their ability to hydrolyze 5-phosphoribosyl 1-pyrophosphate (PRPP). All 11 enzymes… 
Highly Cited
1975
Highly Cited
1975
Technetium-99m-pyrophosphate: studies in vivo and in vitro.
In rats with induced rickets, the uptake of 99mTcO4 and 99mTc-pyrophosphate per gram of bone was increased as compared with… 
1975
1975
Detection of acute myocardial infarction by technetium-99m polyphosphate.
Highly Cited
1974
Highly Cited
1974
Metastatic calcification detected through scanning with 99mTc-polyphosphate.
1974
1974
Clinical correlations of 67Ga and skeletal whole-body radionuclide studies with radiography in Ewing's sarcoma.
Twenty-seven patients with Ewing's sarcoma were evaluated by whole-body radionuclide studies, using 67Ga citrate and 18F or 99mTc… 
Highly Cited
1974
Highly Cited
1974
A proposed mechanism for 99mTc-labeled polyphosphate and diphosphonate uptake by human breast tissue.
Local uptake of 99mTc-polyphosphate or 99mTc-diphosphonate by breast tissue was observed in 17 patients, occurring in normal… 
Highly Cited
1962
Highly Cited
1962
Myoinositol polyphosphate intermediates in the dephosphorylation of phytic acid by phytase.
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