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Ingenol Mebutate Gel

Known as: Ingenol-3-angelate Gel 
A topical, aqueous gel formulation containing the mebutate salt form of ingenol, a selective small-molecule activator of protein kinase C (PKC) that… 
National Institutes of Health

Related topics

Related topics

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NCIt Antineoplastic Agent Terminology

Papers overview

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Review
2016
Review
2016
Treatment of superficial basal cell carcinoma with ingenol mebutate gel, 0.05%
Background Basal cell carcinoma (BCC) is the most common cancer in Caucasians. Surgical approaches are the most widely used and… 
2016
2016
Dermoscopy and Reflectance Confocal Microscopy for Monitoring the Treatment of Actinic Keratosis with Ingenol Mebutate Gel: Report of Two Cases
IntroductionA relatively novel application for dermoscopy and reflectance confocal microscopy (RCM) is their use in the… 
2015
2015
Cosmetic Effects of Ingenol Mebutate Gel in the Treatment of Field-Cancerized Photodamaged Skin.
Figure 1. (A) Scalp of an 82-year-old patient with actinic field cancerization and mottled pigmentation. In the marked area, 1… 
2014
2014
Efficacy and safety of ingenol mebutate 0.015% gel after cryosurgery of actinic keratosis: 12-month results.
INTRODUCTION Recurrence rates of actinic keratosis (AK) lesions after cryosurgery are high, and this treatment does not address… 
2014
2014
Efficacy and safety of ingenol mebutate 0.015% gel 3 weeks after cryosurgery of actinic keratosis: 11-week results.
INTRODUCTION Cryosurgery is the most common treatment for actinic keratosis (AK) in the United States. Efficacy with cryosurgery… 
2014
2014
Superficial basal cell carcinoma successfully treated with ingenol mebutate gel 0.05%
Basal cell carcinoma (BCC) is the most common cancer in the world (1). It is typically slow growing and rarely metastatic… 
Highly Cited
2012
Highly Cited
2012
Ingenol mebutate field-directed treatment of UVB-damaged skin reduces lesion formation and removes mutant p53 patches.
Skin cancer is the most prevalent cancer worldwide and is primarily caused by chronic UV exposure. Here, we describe the topical… 
2012
2012
Ingenol mebutate: an introduction.
The incidence of nonmelanoma skin cancer continues to increase. While surgical excision remains the mainstay of treatment… 
Highly Cited
2009
Highly Cited
2009
PEP005 (ingenol mebutate) gel, a novel agent for the treatment of actinic keratosis: Results of a randomized, double‐blind, vehicle‐controlled, multicentre, phase IIa study
The sap of the plant Euphorbia peplus is a traditional remedy for skin conditions, including actinic keratosis. The active… 
Highly Cited
2009
Highly Cited
2009
Randomized, double-blind, double-dummy, vehicle-controlled study of ingenol mebutate gel 0.025% and 0.05% for actinic keratosis.
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