Inflammasomes

Known as: Pyroptosome, Inflammasome, Inflammasomes [Chemical/Ingredient] 
Multiprotein complexes that mediate the activation of CASPASE-1. Dysregulation of inflammasomes has also been linked to a number of autoinflammatory… (More)
National Institutes of Health

Papers overview

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Review
2017
Review
2017
Inflammation affects all stages of tumorigenesis. A key signaling pathway leading to acute and chronic inflammation is through… (More)
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Review
2017
Review
2017
Necroptosis is a form of regulated cell death, which is induced by ligand binding to TNF family death domain receptors, pattern… (More)
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Review
2017
Review
2017
Autophagy is a ubiquitous cellular mechanism for the targeted lysosomal degradation of various cytosolic constituents, from… (More)
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Review
2017
Review
2017
A growing number of findings highlight the crucial role of metabolic reprogramming in macrophage activation. Metabolic pathways… (More)
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Review
2012
Review
2012
Inflammasomes are multiprotein complexes that activate caspase-1, which leads to maturation of the proinflammatory cytokines… (More)
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Highly Cited
2012
Highly Cited
2012
Autophagosomes delivers cytoplasmic constituents to lysosomes for degradation, whereas inflammasomes are molecular platforms… (More)
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Highly Cited
2012
Highly Cited
2012
Non-alcoholic fatty liver disease (NAFLD) is the hepatic manifestation of metabolic syndrome and the leading cause of chronic… (More)
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Highly Cited
2011
Highly Cited
2011
An inflammatory response initiated by the NLRP3 inflammasome is triggered by a variety of situations of host ‘danger’, including… (More)
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Highly Cited
2008
Highly Cited
2008
Inhalation of silica crystals causes inflammation in the alveolar space. Prolonged exposure to silica can lead to the development… (More)
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Highly Cited
2006
Highly Cited
2006
Development of the acute and chronic inflammatory responses known as gout and pseudogout are associated with the deposition of… (More)
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