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Inflammasomes

Known as: Pyroptosome, Inflammasome, Inflammasomes [Chemical/Ingredient] 
Multiprotein complexes that mediate the activation of CASPASE-1. Dysregulation of inflammasomes has also been linked to a number of autoinflammatory… 
National Institutes of Health

Papers overview

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2018
2018
France; Centre Hospitalier Universitaire Nice, Hôpital l’Archet, Département Digestif, 06200 Nice, France; Université Paris… 
2017
2017
Guanylate binding proteins (GBPs) are interferon-inducible proteins involved in the cellintrinsic immunity against numerous… 
2016
2016
Lung cancer is the leading cause of cancer death, and it is widely accepted that chronic inflammation is an important risk for… 
Review
2016
Review
2016
Inflammasome activation is mediated by (NOD)-like receptors (NLR) proteins that respond to stimuli. Among NLRs, NACHT-LRR and PYD… 
2015
2015
KeY wOrds: s ystemic sclerosis (SSc) is an autoimmune disease that manifests as skin fibrosis, systemic vascular alterations and… 
2015
2015
Kim SM, Lee SH, Kim YG, Kim SY, Seo JW, Choi YW, Kim DJ, Jeong KH, Lee TW, Ihm CG, Won KY, Moon JY. Hyperuricemia-induced NLRP3… 
2014
2014
It is recognized that abdominal obesity is accompanied by a chronic low-grade inflammation that is involved in the pathogenesis… 
2012
2012
The notion that neutrophils play a pivotal role in orchestrating ongoing inflammatory immune responses has been bolstered by… 
2010
2010
The NLRP3 inflammasome protects against tumorigenesis in an experimental mouse model of colitis-associated cancer. 
2007
2007
The inflammasome is a cytosolic protein complex regulating the activation of caspase-1, which cleaves the pro-inflammatory…