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Inflammasomes

Known as: Pyroptosome, Inflammasome, Inflammasomes [Chemical/Ingredient] 
Multiprotein complexes that mediate the activation of CASPASE-1. Dysregulation of inflammasomes has also been linked to a number of autoinflammatory… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2019
Review
2019
The NLRP3 inflammasome is a critical component of the innate immune system that mediates caspase-1 activation and the secretion… Expand
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Review
2019
Review
2019
NLRP3 (NOD-, LRR- and pyrin domain-containing protein 3) is an intracellular sensor that detects a broad range of microbial… Expand
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Review
2019
Review
2019
The NLRP3 inflammasome is a multimeric protein complex that initiates an inflammatory form of cell death and triggers the release… Expand
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Review
2019
Review
2019
Neuroinflammation and neurodegeneration often result from the aberrant deposition of aggregated host proteins, including amyloid… Expand
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Review
2019
Review
2019
Age-associated chronic inflammation is characterized by unresolved and uncontrolled inflammation with multivariable low-grade… Expand
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Review
2019
Review
2019
Inflammasomes are multiprotein innate immune complexes that regulate caspase-dependent inflammation and cell death. Pattern… Expand
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Review
2019
Review
2019
Caspases are an evolutionary conserved family of cysteine proteases that are centrally involved in cell death and inflammation… Expand
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Review
2019
Review
2019
Parkinson's disease (PD) is a typical neurodegenerative disease and the pathological feature of which is the death of dopamine… Expand
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Review
2018
Review
2018
NLRP3 is the most studied inflammasome sensor due to its crucial involvement in sterile and infection-triggered inflammation… Expand
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Review
2018
Review
2018
Canonical functions of mitochondria include the regulation of cellular survival, orchestration of anabolic and metabolic pathways… Expand
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