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A great deal of effort has been made over the years to develop liposomes that have targeting vectors (oligosaccharides, peptides… Expand A sterically stabilized paclitaxel-loaded liposome tailored to target human breast cancer cells was developed, thereby promoting… Expand We describe evidence for a novel mechanism of monoclonal antibody (MAb)-directed nanoparticle (immunoliposome) targeting to solid… Expand We previously reported the development of epidermal growth factor receptor (EGFR)-targeted immunoliposomes that bind and… Expand Nanoscale drug delivery systems including liposomes, polymers, and other nanoparticles provide potential solutions for improved… Expand PURPOSE
Anti-HER2 immunoliposomes combine the tumor-targeting of certain anti-HER2 monoclonal antibodies (MAbs) with the… Expand An ideal therapeutic for cancer would be one that selectively targets to tumor cells, is nontoxic to normal cells, and that could… Expand Immunoliposomes (antibody-directed liposomes) were used in the present study for delivery of the antineoplastic agent daunomycin… Expand Distearoyl-N-(3-carboxypropionoyl poly(ethylene glycol) succinyl)phosphatidylethanolamine (DSPE-PEG-COOH) was newly synthesized… Expand Dioleoyl-N-(monomethoxy polyethyleneglycol succinyl)-phosphatidylethanolamine (PEG-PE) (mol. wt. of PEG = 5000), an amphipathic… Expand