Immunoglobulin M

Known as: Gamma Globulin, 19S, immunoglobulin m (IgM), Immunoglobulin M [Chemical/Ingredient] 
The major immunoglobulin secreted during a primary immune response. IgM binds with low affinity but high avidity (multiple binding sites) because it… (More)

Topic mentions per year

Topic mentions per year

1944-2017
0500100019442016

Papers overview

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Review
2015
Review
2015
Complement is increasingly being recognized as an important driver of human disease, including many hemolytic anemias. Paroxysmal… (More)
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Highly Cited
2004
Highly Cited
2004
The human peripheral B-cell compartment displays a large population of immunoglobulin M-positive, immunoglobulin D-positive CD27… (More)
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Highly Cited
2003
Highly Cited
2003
Splenectomized and asplenic patients have a high incidence of infections by encapsulated bacteria and do not respond to… (More)
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Highly Cited
2003
Highly Cited
2003
OBJECTIVE To evaluate the prevalence and predictive value of anti-cyclic citrullinated peptide (anti-CCP) antibodies in… (More)
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Highly Cited
2000
Highly Cited
2000
Induced overexpression of AID in CH12F3-2 B lymphoma cells augmented class switching from IgM to IgA without cytokine stimulation… (More)
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Highly Cited
2000
Highly Cited
2000
We have studied the role of secreted immunoglobulin (Ig)M in protection from infection with influenza virus and delineated the… (More)
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Highly Cited
1998
Highly Cited
1998
Immunoglobulin (Ig)M+IgD+ B cells are generally assumed to represent antigen-inexperienced, naive B cells expressing variable (V… (More)
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Highly Cited
1998
Highly Cited
1998
To evaluate the role of natural immunoglobulin (Ig)M in the immediate response against microbial infection, we tested mutant mice… (More)
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Highly Cited
1991
Highly Cited
1991
Of the various classes of antibodies that B lymphocytes can produce, class M (IgM) is the first to be expressed on the membrane… (More)
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Highly Cited
1988
Highly Cited
1988
Immunological tolerance has been demonstrated in double-transgenic mice expressing the genes for a neo-self antigen, hen egg… (More)
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