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Immunoglobulin M

Known as: Gamma Globulin, 19S, immunoglobulin m (IgM), Immunoglobulin M [Chemical/Ingredient] 
The major immunoglobulin secreted during a primary immune response. IgM binds with low affinity but high avidity (multiple binding sites) because it… 
National Institutes of Health

Related topics

Related topics

50 relations
AntibodiesBabesia microti Ab.IgM:ACnc:Pt:Ser:QnBacteroides fragilis Ab.IgM:ACnc:Pt:Ser:QnBarmah forest virus Ab.IgM:PrThr:Pt:Ser:Ord

Narrower (2)

IgM-L paraproteinIgM1

Papers overview

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Highly Cited
1996
Highly Cited
1996
Modulation of natural IgM binding and complement activation by natural IgG antibodies: a role for IgG anti-Gal alpha1-3Gal antibodies.
The most abundant natural IgG Abs in human serum are thought to be Abs specific for Gal alpha1-3Gal, a carbohydrate expressed in… 
Highly Cited
1988
Highly Cited
1988
Human recombinant IL-4 induces activated B lymphocytes to produce IgG and IgM.
In this report, we describe a novel biologic activity of IL-4 namely, its ability to induce activated human B cells to produce… 
Highly Cited
1987
Highly Cited
1987
Serum antibodies to cow's milk proteins in ulcerative colitis and Crohn's disease.
Highly Cited
1987
Highly Cited
1987
Idiotype vaccination against murine B cell lymphoma. Humoral and cellular responses elicited by tumor-derived immunoglobulin M and its molecular subunits.
C3H/HeN mice were immunized with idiotypic immunoglobulin M (IgM) and its molecular subunits from the syngeneic 38C13 lymphoma… 
Highly Cited
1986
Highly Cited
1986
Functional characterization of human IgG, IgM, and IgA antibody directed to the capsule of Haemophilus influenzae type b.
Antibody to the capsular polysaccharide (CP) of Haemophilus influenzae b (Hib) is bactericidal, opsonic, and protective. Minimum… 
Highly Cited
1984
Highly Cited
1984
The molecular biology of immunoglobulin D
Immunoglobulin D (IgD) is co-expressed with immunoglobulin M (IgM) on the membranes of most B cells, yet its biological function… 
Highly Cited
1979
Highly Cited
1979
Hyper immunoglobulin M immunodeficiency. (Dysgammaglobulinemia). Presence of immunoglobulin M-secreting plasmacytoid cells in peripheral blood and failure of immunoglobulin M-immunoglobulin G switch…
The peripheral blood lymphocytes of nine patients with hyper immunoglobulin (Ig)M immunodeficiency were studied in an attempt to… 
Highly Cited
1975
Highly Cited
1975
Hereditary complement (C2) deficiency with dermatomyositis.
Highly Cited
1974
Highly Cited
1974
Recognition of Two Distinct Groups of Human IgM and IgA Based on Different Binding to Staphylococci
Labeled monoclonal IgM was bound to the Cowan I strain of Staphylococcus aureus in the absence of anti‐IgM antibody This binding… 
Highly Cited
1968
Highly Cited
1968
The Wiskott-Aldrich syndrome. A disorder with a possible defect in antigen processing or recognition.
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