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Immune complex

Known as: Immune complexes, Antigen-Antibody Complexes, complexes immune 
The complex formed by the binding of antigen and antibody molecules. The deposition of large antigen-antibody complexes leading to tissue damage… Expand
National Institutes of Health

Related topics

Related topics

18 relations

Broader (2)

Antigen-Antibody ReactionsImmunologic Factors
Arthus ReactionCandida albicans immune complex:ACnc:Pt:Ser/Plas:QnCirculating Immune Complex MeasurementImmune Complex Diseases
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Papers overview

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Highly Cited
2007
Highly Cited
2007
Toll-like receptor 9–dependent activation by DNA-containing immune complexes is mediated by HMGB1 and RAGE
Increased concentrations of DNA-containing immune complexes in the serum are associated with systemic autoimmune diseases such as… Expand
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Highly Cited
2006
Highly Cited
2006
Selective Stimulation of T Cell Subsets with Antibody-Cytokine Immune Complexes
Interleukin-2 (IL-2), which is a growth factor for T lymphocytes, can also sometimes be inhibitory. Thus, the proliferation of… Expand
Highly Cited
2003
Highly Cited
2003
Probing Biomolecular Interactions at Conductive and Semiconductive Surfaces by Impedance Spectroscopy: Routes to Impedimetric Immunosensors, DNA‐Sensors, and Enzyme Biosensors
Impedance spectroscopy is a rapidly developing electrochemical technique for the characterization of biomaterialfunctionalized… Expand
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Review
2003
Review
2003
Evolving concepts of rheumatoid arthritis
Rheumatoid arthritis is the most common inflammatory arthritis and is a major cause of disability. It existed in early Native… Expand
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Highly Cited
2002
Highly Cited
2002
Chromatin–IgG complexes activate B cells by dual engagement of IgM and Toll-like receptors
Autoreactive B cells are present in the lymphoid tissues of healthy individuals, but typically remain quiescent. When this… Expand
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Highly Cited
1999
Highly Cited
1999
Fcγ Receptor–mediated Induction of Dendritic Cell Maturation and Major Histocompatibility Complex Class I–restricted Antigen Presentation after Immune Complex Internalization
Dendritic cells (DCs) express several receptors for the Fc portion of immunoglobulin (Ig)G (FcγR), which mediate internalization… Expand
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Highly Cited
1998
Highly Cited
1998
Uncoupling of immune complex formation and kidney damage in autoimmune glomerulonephritis.
The generation of autoantibody and subsequent tissue deposition of immune complexes (IC) is thought to trigger the pathogenic… Expand
Highly Cited
1985
Highly Cited
1985
Measurements of the true affinity constant in solution of antigen-antibody complexes by enzyme-linked immunosorbent assay.
A simple, general procedure is described for the determination of the dissociation constant (KD) of antigen-antibody equilibria… Expand
Highly Cited
1984
Highly Cited
1984
Immunoenzymatic labeling of monoclonal antibodies using immune complexes of alkaline phosphatase and monoclonal anti-alkaline phosphatase (APAAP complexes).
A murine monoclonal antibody specific for calf intestinal alkaline phosphatase has been prepared and used in an unlabeled… Expand
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Highly Cited
1981
Highly Cited
1981
"Western blotting": electrophoretic transfer of proteins from sodium dodecyl sulfate--polyacrylamide gels to unmodified nitrocellulose and radiographic detection with antibody and radioiodinated…
A simple and efficient procedure was employed for the electrophoretic transfer of proteins from sodium dodecyl sulfate… Expand
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