Iduronate Sulfatase

Known as: Sulfatase, Sulfoiduronate, Hunter Corrective Factor, Sulfatase, Iduronate 
An enzyme that specifically cleaves the ester sulfate of iduronic acid. Its deficiency has been demonstrated in Hunter's syndrome, which is… (More)
National Institutes of Health

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Highly Cited
2010
Highly Cited
2010
To investigate the pedagogical effectiveness of oral corrective feedback (CF) on target language development, we conducted a… (More)
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2008
2008
Molecular defects in the gene encoding the enzyme iduronate-2-sulfatase (IDS) result in Hunter disease (mucopolysaccharidosis… (More)
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2007
2007
Sulfatase enzymes have important roles in metabolism of steroid hormones and of glycosaminoglycans (GAGs). The activity of five… (More)
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1998
1998
Genomic DNA from 57 unrelated MPS II (Hunter's disease) patients was analysed for mutations of the iduronate sulphatase (IDS… (More)
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1993
1993
Iduronate sulfatase (IDS; EC 3.1.6.13) is a lysosomal enzyme that acts on sulfate groups on C-2 positions of iduronic acid… (More)
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Highly Cited
1990
Highly Cited
1990
Iduronate 2-sulfatase (IDS, EC 3.1.6.13) is required for the lysosomal degradation of heparan sulfate and dermatan sulfate… (More)
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1978
1978
Iduronate sulfatase, the enzyme deficient in Hunter syndrome, can be readily measured in individual hair roots. Samples from… (More)
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1977
1977
Profound iduronate sulfatase deficiency, characteristic of the Hunter syndrome, has been found in cultured fibroblasts, serum… (More)
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1976
1976
Extract: A previously described assay for iduronate sulfatase has been adapted for use with serum, lymphocytes, and fibroblasts… (More)
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Highly Cited
1973
Highly Cited
1973
Skin fibroblasts cultured from patients affected with the Hunter syndrome are deficient in the activity of a protein, named the… (More)
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