Mucopolysaccharidosis II

Known as: MPS2, SIDS DEFICIENCY, Hunter's syndrome 
An X-linked, inherited lysosomal storage disease caused by the deficiency of the enzyme iduronate sulfatase that is responsible for the degradation… (More)
National Institutes of Health

Papers overview

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Highly Cited
2015
Highly Cited
2015
We extend the scope of European palaeogenomics by sequencing the genomes of Late Upper Palaeolithic (13,300 years old, 1.4-fold… (More)
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Highly Cited
2010
Highly Cited
2010
This open-label clinical study enrolled 10 adults with attenuated Mucopolysaccharidosis II and advanced disease under the… (More)
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Highly Cited
2007
Highly Cited
2007
OBJECTIVE To evaluate the safety and explore the efficacy of idursulfase (recombinant human iduronate-2-sulfatase) treatment for… (More)
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Highly Cited
2006
Highly Cited
2006
Purpose: To evaluate the safety and efficacy of recombinant human iduronate-2-sulfatase (idursulfase) in the treatment of… (More)
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Highly Cited
2004
Highly Cited
2004
Strain typing using variable-number tandem repeats of mycobacterial interspersed repetitive units (MIRU-VNTR) is a powerful tool… (More)
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Review
2002
Review
2002
Mucopolysaccharidosis type II (MPS II; Hunter syndrome) is an X-linked disease caused by a deficiency of the enzyme iduronate-2… (More)
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Highly Cited
1991
Highly Cited
1991
It is crucial to the eucaryotic cell cycle that the centrosome undergo precise duplication to generate the two poles of the… (More)
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Highly Cited
1987
Highly Cited
1987
Two potent and highly selective nonpeptide antagonists, L-365,031 [1-methyl-3-(4-bromobenzoyl)amino-5-phenyl-3H-1,4 benzodiazepin… (More)
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1986
1986
Tooth fragments are an appreciable but neglected proportion of fossil hominid specimens. The present study on 47 naturally… (More)
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1982
1982
Comparison of the disease course in patients with the severe and mild forms of Hunter's syndrome indicates that the severely… (More)
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