idursulfase

Known as: Alpha-L-iduronate sulfate sulfatase, idursulfase [Chemical/Ingredient] 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

2006-2016
0520062016

Papers overview

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2016
2016
Purpose:Approximately two-thirds of patients with the lysosomal storage disease mucopolysaccharidosis II have progressive… (More)
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2013
2013
BACKGROUND Mucopolysaccharidosis II (MPS II, Hunter syndrome) is a rare X-linked lysosomal storage disorder caused by the… (More)
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2012
2012
A major challenge for the treatment of many central nervous system (CNS) disorders is the lack of convenient and effective… (More)
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Highly Cited
2011
Highly Cited
2011
Purpose: This study evaluated the safety and effectiveness of long-term enzyme replacement therapy with idursulfase (recombinant… (More)
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2011
2011
Recombinant human idursulfase, an intravenous enzyme replacement therapy indicated for treatment of somatic symptoms of… (More)
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2010
2010
This open-label clinical study enrolled 10 adults with attenuated Mucopolysaccharidosis II and advanced disease under the… (More)
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2008
2008
We present a 3-year-old boy affected with Hunter syndrome. When we first evaluated the patient glycosaminoglycans (GAG) in urine… (More)
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2007
2007
Mucopolysaccharidosis II (MPS II; Hunter syndrome) is an X-linked metabolic disorder caused by a deficiency of the lysosomal… (More)
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Highly Cited
2007
Highly Cited
2007
OBJECTIVE To evaluate the safety and explore the efficacy of idursulfase (recombinant human iduronate-2-sulfatase) treatment for… (More)
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Highly Cited
2006
Highly Cited
2006
Purpose: To evaluate the safety and efficacy of recombinant human iduronate-2-sulfatase (idursulfase) in the treatment of… (More)
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