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ITSN1 wt Allele

Known as: Human Intersectin-SH3 Domain-Containing Protein SH3P17 Gene, SH3D1A, ITSN 
Human ITSN1 wild-type allele is located within 21q22.1-q22.2 and is approximately 257 kb in length. This allele, which encodes intersectin-1 protein… 
National Institutes of Health

Related topics

Related topics

3 relations
EndocytosisSignal Transductionprotein protein interaction

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2010
2010
Autoinhibition of GEF activity in intersectin 1 is mediated by the short SH3‐DH domain linker
Intersectin 1L (ITSN1L) acts as a specific guanine nucleotide exchange factor (GEF) for the small guanine nucleotide binding… 
Highly Cited
2007
Highly Cited
2007
Regulation of Neuron Survival through an Intersectin-Phosphoinositide 3′-Kinase C2β-AKT Pathway
ABSTRACT While endocytosis attenuates signals from plasma membrane receptors, recent studies suggest that endocytosis also serves… 
Review
2007
Review
2007
Intersectin enhances huntingtin aggregation and neurodegeneration through activation of c-Jun-NH2-terminal kinase.
Huntingon's disease is a progressive neurodegenerative disease arising from expansion of a polyglutamine (polyQ) tract in the… 
Highly Cited
2004
Highly Cited
2004
Detaching thiolates from copper and gold clusters: which bonds to break?
The interaction of alkanethiolates with small coinage metal clusters of copper and gold was studied based on density functional… 
Highly Cited
2003
Highly Cited
2003
Intersectin Activates Ras but Stimulates Transcription through an Independent Pathway Involving JNK*
Intersectin (ITSN) is a molecular scaffold involved in regulating endocytosis and mitogenic signaling. We previously demonstrated… 
2001
2001
New evidence for a subshell gap at N = 32
  • 2001
  • Corpus ID: 37244571
An 879.9(2) keVγ -ray transition has been identified following the β decay of58V and assigned as the 2 1 → 01 transition in Cr34… 
Highly Cited
1999
Highly Cited
1999
Alu-splice cloning of human Intersectin (ITSN), a putative multivalent binding protein expressed in proliferating and differentiating neurons and overexpressed in Down syndrome
By Alu-splice PCR we have trapped two exons and subsequently identified the full length cDNA of a human gene, Intersectin (ITSN… 
Highly Cited
1998
Highly Cited
1998
Two isoforms of a human intersectin (ITSN) protein are produced by brain-specific alternative splicing in a stop codon.
Using selected trapped exons with homology to specific protein domains, we identified a new full-length cDNA encoding a protein… 
1988
1988
Genotoxic activities of benzamidine and itsN-hydroxylated metabolite benzamidoxime inSalmonella typhimurium and mammalian cells
SummaryThe genotoxic potentials of benzamidine and benzamidoxime were determined to study the toxicological relevance of the… 
1970
1970
Isolation of UDP‐N‐glycolylmuramyl‐(Ala, Glu, DAP) from mycobacterium phlei
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