ITPR1 protein, human

Known as: Type 1 InsP3 Receptor, SCA15 protein, human, IP3R 
Inositol 1,4,5-trisphosphate receptor type 1 (2758 aa, ~314 kDa) is encoded by the human ITPR1 gene. This protein is involved in intracellular… (More)
National Institutes of Health

Papers overview

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Review
2014
Review
2014
Endoplasmic reticulum (ER) stress plays an important role in a range of neurological disorders, such as neurodegenation diseases… (More)
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Highly Cited
2012
Highly Cited
2012
Antiapoptotic B-cell lymphoma 2 (Bcl-2) targets the inositol 1,4,5-trisphosphate receptor (IP3R) via its BH4 domain, thereby… (More)
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Highly Cited
2010
Highly Cited
2010
Different physiological and pathological conditions can perturb protein folding in the endoplasmic reticulum, leading to a… (More)
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2007
2007
Embryonic stem cell-derived cardiomyocytes (ESdCs) have been proposed as a source for cardiac cell-replacement therapy. The aim… (More)
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2006
2006
We describe a finite-element model of mast cell calcium dynamics that incorporates the endoplasmic reticulum's complex geometry… (More)
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Highly Cited
2005
Highly Cited
2005
Recent studies have suggested that inositol-1,4,5-trisphosphate-receptor (IP3R)-mediated Ca2+ release plays an important role in… (More)
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Highly Cited
2005
Highly Cited
2005
A key aspect of postsynaptic function, also important for plasticity, is the segregation within dendritic spines of Ca2+ rises… (More)
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1997
1997
Chronic stimulation of WB rat liver epithelial cells by angiotensin II (Ang II) resulted in the down-regulation of both type I… (More)
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1993
1993
Calcium release from intracellular stores is the signal generated by numerous regulatory pathways including those mediated by… (More)
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Highly Cited
1993
Highly Cited
1993
The expression of inositol 1,4,5-trisphosphate receptor type 1 (InsP3R1) in the mouse central nervous system (CNS) was studied by… (More)
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