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ITPR1 protein, human

Known as: Type 1 InsP3 Receptor, SCA15 protein, human, IP3R 
Inositol 1,4,5-trisphosphate receptor type 1 (2758 aa, ~314 kDa) is encoded by the human ITPR1 gene. This protein is involved in intracellular… 
National Institutes of Health

Related topics

Related topics

17 relations
Alzheimer's Disease Pathway KEGGCalcium BindingCalcium SignalingITPR1 gene

Broader (2)

inositol 1,4,5-trisphosphate receptor type 1inositol-1,4,5-triphosphate receptor

Papers overview

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2016
2016
Sulforaphane-induced apoptosis involves the type 1 IP3 receptor
In this study we show that anti-tumor effect of sulforaphane (SFN) is partially realized through the type 1 inositol 1,4,5… 
Review
2015
Review
2015
Bcl-2 and FKBP12 bind to IP3 and ryanodine receptors at overlapping sites: the complexity of protein-protein interactions for channel regulation.
The 12- and 12.6-kDa FK506-binding proteins, FKBP12 (12-kDa FK506-binding protein) and FKBP12.6 (12.6-kDa FK506-binding protein… 
Review
2012
Review
2012
Synaptopodin and the spine apparatus organelle-regulators of different forms of synaptic plasticity?
2009
2009
Effects of zonisamide on neurotransmitter release associated with inositol triphosphate receptors
2007
2007
Proteomic and biochemical studies of calcium- and phosphorylation-dependent calmodulin complexes in Mammalian cells.
Protein conformational changes due to cofactor binding (e.g., metal ions, heme) and/or post-translational modifications (e.g… 
2006
2006
Reactivity of free thiol groups in type-I inositol trisphosphate receptors.
The IP3R (inositol 1,4,5-trisphosphate receptor) Ca2+-release channel is known to be sensitive to thiol redox state. The present… 
2006
2006
Endogenously Bound Calmodulin Is Essential for the Function of the Inositol 1,4,5-Trisphosphate Receptor*
Calmodulin (CaM) is a ubiquitous Ca2+ sensor protein that plays an important role in regulating a large number of Ca2+ channels… 
Highly Cited
2005
Highly Cited
2005
Homer modulates NFAT-dependent signaling during muscle differentiation.
Highly Cited
1992
Highly Cited
1992
Plasma membrane inositol 1,4,5-trisphosphate receptor of lymphocytes: selective enrichment in sialic acid and unique binding specificity.
The inositol 1,4,5-trisphosphate receptor (IP3R) associated with plasma membranes of lymphocytes differs in terminal sugar… 
Highly Cited
1992
Highly Cited
1992
Inositol 1,4,5-trisphosphate receptors. Localization in epithelial tissue.
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