Skip to search formSkip to main contentSkip to account menu

ITGAM protein, human

Known as: MAC1 Alpha, CD11b, Integrin Alpha-M 
Integrin alpha-M (1152 aa, ~127 kDa) is encoded by the human ITGAM gene. This protein is involved in both leukocyte adhesion and the phagocytosis of… 
National Institutes of Health

Related topics

Related topics

14 relations
CD11B Expressing Cell CountCell AdhesionClusters of differentiationGlycoproteins

Broader (1)

CD11b Antigens

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
The NF-kB regulates the SHP-1 expression in monocytes in congestive heart failure.
It has been shown that functional recovery of patients with acute congestive heart failure (ACHF) after treatment with… 
2017
2017
Systemic lupus erythematosus: Defective CD11b raises IFN levels in SLE
Genetic variants of ITGAM that produce integrin αM (also known as CD11b) with reduced activity are associated with increased… 
2012
2012
Effects of cryopreservation with polyethylene glycol on the expression of CD11b and CD62L on the surface of polymorphonuclear leukocytes.
In experimental and clinical studies, expression of surface adhesion molecules such as ß2-integrine (CD11b) and L-selectin (CD62L… 
2003
2003
Brief hypoxia conditions monocytes to protect reperfused cardiocytes against cell death via the CD11b receptor.
2002
2002
Regulation of adhesion of AML14.3D10 cells by surface clustering of β2‐integrin caused by ERK‐independent activation of cPLA2
We examined the role of cell surface clustering of β2‐integrin caused by protein kinase C (PKC)‐activated‐cPLA2 in adhesion of… 
1999
1999
Blood levels of CD11bH+ memory T lymphocytes are selectively upregulated in patients with active rheumatoid arthritis
The adhesion molecules CD11b (a β2‐integrin component) and CD54 (ICAM‐1) on blood leukocytes were studied by flow cytometry in… 
1998
1998
[The effect of PMN adhesion mediated by CD11b/CD18 on the increasing permeability of microvascular endothelial monolayer after severe burn injury].
OBJECTIVE To detect the effect of burn-activated PMN adhesion and its adhesion molecule CD11b/CD18 on microvascular endothelial… 
1994
1994
Lipopolysaccharide-induced CD11B-mediated neutrophil-endothelial adhesion is not required for polymorphonuclear cell priming.
Previous work has implicated both neutrophil-endothelial cell (PMN-EC) adhesion and PMN priming (enhanced superoxide production… 
Highly Cited
1992
Highly Cited
1992
Leucocyte adhesion protein deficiency in Irish setter dogs.
1989
1989
cDNA sequence for the alpha M subunit of the human neutrophil adherence receptor indicates homology to integrin alpha subunits.
The receptor on human neutrophils (polymorphonuclear leukocytes) that mediates cellular adherence consists of two noncovalently… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)