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ITGAM gene

Known as: CD11b, INTEGRIN, ALPHA-M, ITGAM 
This gene plays a role in extracellular matrix interactions and cellular adhesion.
National Institutes of Health

Papers overview

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Highly Cited
2014
Highly Cited
2014
We performed a genome-wide association study (GWAS) of IgA nephropathy (IgAN), the most common form of glomerulonephritis, with… Expand
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Highly Cited
2012
Highly Cited
2012
Objectives The rs1143679 variant of ITGAM, encoding the R77H variant of CD11b (part of complement receptor 3; CR3), is among the… Expand
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Highly Cited
2011
Highly Cited
2011
Systemic lupus erythematosus (SLE) is a clinically heterogeneous, systemic autoimmune disease characterized by autoantibody… Expand
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Review
2010
Review
2010
Our understanding of the genetic basis of systemic lupus erythematosus (SLE) has been rapidly advanced using large-scale, case… Expand
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Highly Cited
2010
Highly Cited
2010
Purpose It was hypothesised that the coding variant (R77H), rs1143679, within ITGAM could predict specific clinical… Expand
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Highly Cited
2009
Highly Cited
2009
We recently identified a novel non-synonymous variant, rs1143679, at exon 3 of the ITGAM gene associated with systemic lupus… Expand
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Highly Cited
2009
Highly Cited
2009
ITGAM was recently found to be associated with systemic lupus erythematosus (SLE) in populations of not only European ancestry… Expand
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Highly Cited
2008
Highly Cited
2008
Systemic lupus erythematosus (SLE) is a common systemic autoimmune disease with complex etiology but strong clustering in… Expand
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Highly Cited
2008
Highly Cited
2008
BACKGROUND Systemic lupus erythematosus (SLE) is a clinically heterogeneous disease in which the risk of disease is influenced by… Expand
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Highly Cited
2008
Highly Cited
2008
We identified and replicated an association between ITGAM (CD11b) at 16p11.2 and risk of systemic lupus erythematosus (SLE) in 3… Expand
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