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ITGAM gene

Known as: CD11b, INTEGRIN, ALPHA-M, ITGAM 
This gene plays a role in extracellular matrix interactions and cellular adhesion.
National Institutes of Health

Related topics

Related topics

10 relations
ApoptosisCD11b AntigensCell AdhesionChemotaxis

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ITGAM wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Association of ITGAM, TNFSF4, TNFAIP3 and STAT4 gene polymorphisms with risk of systemic lupus erythematosus in a North Indian population
Several susceptibility genes have been associated with systemic lupus erythematosus (SLE) across different populations worldwide… 
2018
2018
Modulation of human Th17 cell responses through complement receptor 3 (CD11 b/CD18) ligation on monocyte-derived dendritic cells.
2015
2015
Erratum to: Association between the functional ITGAM rs1143679 G/A polymorphism and systemic lupus erythematosus/lupus nephritis or rheumatoid arthritis: an update meta-analysis
The aim of this study was to determine whether the functional integrin-α-M (ITGAM) rs1143679 polymorphism is associated with… 
2014
2014
Resequencing the susceptibility gene, ITGAM, identifies two functionally deleterious rare variants in systemic lupus erythematosus cases
IntroductionThe majority of the genetic variance of systemic lupus erythematosus (SLE) remains unexplained by the common disease… 
2014
2014
The variant of CD11b, rs1143679 within ITGAM, is associated with systemic lupus erythematosus and clinical manifestations in Brazilian patients.
2011
2011
ITGAM Arg77His is associated with disease susceptibility, arthritis, and renal symptoms in systemic lupus erythematosus patients from a sample of the Polish population.
The ITGAM Arg77His (rs1143679) and Ala858Val (rs1143683) polymorphisms have been found to be strong contributors to systemic… 
2011
2011
A Nonsynonymous Functional Variant of the ITGAM Gene Is Not Involved in Biopsy-proven Giant Cell Arteritis
Objective. To investigate whether a functional integrin alpha M (ITGAM) variant is involved in susceptibility to and clinical… 
Review
2010
Review
2010
Current advances in lupus genetic and genomic studies in Asia
The genetic components in systemic lupus erythematosus (SLE) have long been established, however, it has been unclear for many… 
2006
2006
Detection of constitutive heterodimerization of the integrin Mac-1 subunits by fluorescence resonance energy transfer in living cells.
2006
2006
CD11b is required for the resolution of inflammation induced by Bordetella bronchiseptica respiratory infection
CD11b is a cell surface receptor that contributes to many cellular processes which are involved in the generation of a protective… 
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