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IT-101

Known as: Camptothecin-Polymer Conjugate IT-101 
National Institutes of Health

Related topics

Related topics

3 relations

Narrower (1)

CRLX101

Broader (2)

CamptothecinCyclodextrins

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2010
2010
423 Phase 1 dose escalation, safety and pharmacokinetic study of IT-101 (CRLX101), a novel nanopharmaceutical containing camptothecin, in advanced solid tumor cancer patients
2008
2008
A dose-finding pharmacokinetic study of IT-101, the first de novo designed nanoparticle therapeutic, in refractory solid tumors
Background: IT-101 is the first de novo designed experimental nanoparticle therapeutic for cancer and is comprised of a… 
2007
2007
Preclinical Results of the Camptothecin-Polymer Conjugate IT-101 in Multiple Human Lymphoma Xenografts.
Camptothecin (CPT), a natural alkaloid isolated from Camptotheca acuminata , has potent broad spectrum antitumor activity by… 
2006
2006
Preclinical Efficacy of Campthothecin-Polymer Conjugate (IT-101) in Human Burkitt Lymphoma Bearing Mice.
First line combination chemotherapy can result in long-term disease-free survival (DFS) in 65–90% of patients with Burkitt… 
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