Cyclodextrins

Known as: Cyclomaltooligosaccharides, Cycloamylose, Derivatives, Cyclodextrin 
A homologous group of cyclic GLUCANS consisting of alpha-1,4 bound glucose units obtained by the action of cyclodextrin glucanotransferase on starch… (More)
National Institutes of Health

Related topics

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30 relations

Narrower (20)

2-O-(2-hydroxypropyl)cyclomaltoheptaose6-deoxy-6-fluorocyclomaltoheptaoseADVASEP 7Chirasil-Dex
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Broader (2)

DextrinsGlucans
In BloodProcess of secretionagonistsantagonists & inhibitors
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Papers overview

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Highly Cited
2009
Highly Cited
2009
The first targeted delivery of siRNA in humans via a self-assembling, cyclodextrin polymer-based nanoparticle: from concept to clinic.
Experimental therapeutics developed to exploit RNA interference (RNAi) are now in clinical studies. Here, the translation from… (More)
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Review
2007
Review
2007
Cyclodextrins and their pharmaceutical applications.
Cyclodextrins were first described by Villiers in 1891. Schardinger laid the foundation of the cyclodextrin chemistry in 1903… (More)
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Review
2005
Review
2005
Cyclodextrins in drug delivery.
Cyclodextrins are a family of cyclic oligosaccharides with a hydrophilic outer surface and a lipophilic central cavity… (More)
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Highly Cited
2005
Highly Cited
2005
Evaluation of cyclodextrin solubilization of drugs.
The most common stoichiometry of drug/cyclodextrin complexes is 1:1, i.e. one drug molecule forms a complex with one cyclodextrin… (More)
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Highly Cited
2004
Highly Cited
2004
Past , present , and future of cyclodextrin research *
The macrocyclic cyclodextrins (enzymic conversion products of starch) were discovered in 1891, and the structures were elucidated… (More)
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Review
2001
Review
2001
Cyclodextrins in topical drug formulations: theory and practice.
Cyclodextrins are cyclic oligosaccharides with a hydrophilic outer surface and a somewhat lipophilic central cavity… (More)
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Highly Cited
1999
Highly Cited
1999
Extraction of cholesterol with methyl-beta-cyclodextrin perturbs formation of clathrin-coated endocytic vesicles.
The importance of cholesterol for endocytosis has been investigated in HEp-2 and other cell lines by using methyl-beta… (More)
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Highly Cited
1998
Highly Cited
1998
Effects of cholesterol depletion by cyclodextrin on the sphingolipid microdomains of the plasma membrane.
Sphingolipid microdomains are thought to result from the organization of plasma membrane sphingolipids and cholesterol into a… (More)
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Highly Cited
1997
Highly Cited
1997
Use of cyclodextrins for manipulating cellular cholesterol content.
Previous studies from this laboratory have demonstrated that exposure of tissue culture cells to cyclodextrins results in rapid… (More)
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Highly Cited
1989
Highly Cited
1989
Differential effects of alpha-, beta- and gamma-cyclodextrins on human erythrocytes.
Alpha-, beta- and gamma-cyclodextrins are cyclic hexamers, heptamers, and octamers of glucose, respectively, and thus are… (More)
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