ISCOMs

Known as: ISCOMs [Chemical/Ingredient], ISCOM, Immuno Stimulating Complexes 
A formulation for presenting an antigen to induce specific immunologic responses. It consists of an assembly of antigens in multimeric form. The… (More)
National Institutes of Health

Papers overview

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Review
2001
Review
2001
The immunostimulating complex (ISCOM) is documented as a strong adjuvant and delivery system for parenteral immunization. Its… (More)
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2000
2000
We previously reported that DNA vaccination was able to elicit cellular immune responses and partial protection against Chlamydia… (More)
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Review
1999
Review
1999
The iscom is a uniform stable complex consisting of cholesterol, phospholipid, adjuvant-active saponin, and antigen. The iscom… (More)
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Review
1998
Review
1998
The iscom is a delivery system, designed for both parenteral and mucosal modes of administration, for both antigens and adjuvants… (More)
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1997
1997
The immune stimulating complex (iscom) is built up by antigen, cholesterol, phospholipids, and adjuvant active Quillaja saponins… (More)
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1995
1995
We examined the ability of oral or parenteral immunization with immune stimulating complexes containing ovalbumin (ISCOMS-OVA) to… (More)
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1992
1992
Studies were undertaken in mice using immune-stimulating complexes (ISCOMs) or micelles prepared from envelope glycoproteins of… (More)
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Highly Cited
1990
Highly Cited
1990
To reduce the risks of immunization with killed or live attenuated virus vaccines, it may be advantageous to use a pure, defined… (More)
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1988
1988
A monovalent experimental ISCOM vaccine has been prepared with the envelope glycoproteins haemagglutinin and neuraminidase of the… (More)
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Highly Cited
1984
Highly Cited
1984
We describe here a novel type of immunostimiilating complex, called ‘iscom’, in which virus membrane proteins are presented in a… (More)
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