PICKCa
National Institutes of Health
Papers overview
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The composition of Pamica (PICNH2Ca2) is dsRNA polyI:C, non-biotics amino compounds and CaCl2. It is the second generation…
Objective
To test the immune therapeutic effects of PICKCa adjuvant rabies vaccine for the post-exposure mice and beagle dogs…
皮卡是人用安全的疫苗佐剂，是双链聚肌苷酸聚胞苷酸及微量卡那霉素和氯化钙的复合物。该佐剂是三种模式识别受体TLR3、NOD和RIG-1的配体。皮卡佐剂疫苗与受体结合后在体内活化非特异免疫，包括巨噬细胞吞噬功能，促进干扰素(IFN)、白细胞介素-2(IL-2…
PICKCa, a safe vaccine adjuvant for human use, is a complex of poly IC-kanamycin-Cacl2. It is the li- gand of pattern recognition…
dsRNA adjuvants include PIC, PICLC, PIC12U (Trade name Ampligen) and PICKCa® (PIC-kanamycinCacl2). They are ligands of varied…
As a conjugate of poly I,poly C,kanamycin(K)and calcium chloride(Ca),PICKCa is a safe and effective interferon inducer.The safety…
The rabies vaccine using PICKCa adjuvant has been licensed for clinical study.The vaccine shows good protective effect which is…
SummaryThe activity of an immunostimulatory complex (PICKCa) which is widely used against several human diseases in China was…