PICKCa
National Institutes of Health
Papers overview
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The composition of Pamica (PICNH2Ca2) is dsRNA polyI:C, non-biotics amino compounds and CaCl2. It is the second generation…
Objective
To test the immune therapeutic effects of PICKCa adjuvant rabies vaccine for the post-exposure mice and beagle dogs…
皮卡是人用安全的疫苗佐剂，是双链聚肌苷酸聚胞苷酸及微量卡那霉素和氯化钙的复合物。该佐剂是三种模式识别受体TLR3、NOD和RIG-1的配体。皮卡佐剂疫苗与受体结合后在体内活化非特异免疫，包括巨噬细胞吞噬功能，促进干扰素(IFN)、白细胞介素-2(IL-2…
PICKCa, a safe vaccine adjuvant for human use, is a complex of poly IC-kanamycin-Cacl2. It is the li- gand of pattern recognition…
dsRNA adjuvants include PIC, PICLC, PIC12U (Trade name Ampligen) and PICKCa® (PIC-kanamycinCacl2). They are ligands of varied…
The rabies vaccine using PICKCa adjuvant has been licensed for clinical study.The vaccine shows good protective effect which is…
As a conjugate of poly I,poly C,kanamycin(K)and calcium chloride(Ca),PICKCa is a safe and effective interferon inducer.The safety…