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ISCOMATRIX

National Institutes of Health

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5 relations

Broader (5)

CholesterolDrug CombinationsPhospholipidsSaponins

Papers overview

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2014
2014
The role of surface charge of ISCOMATRIX nanoparticles on the type of immune response generated against Leishmaniasis in BALB/c mice
Objective(s): It is proposed that particulate antigens could better interact with the antigen presenting cells (APCs). A fast… 
2013
2013
Immune response of calves inoculated with proteins of Anaplasma marginale bound to an immunostimulant complex.
Despite our current knowledge of the immunology, pathology, and genetics of Anaplasma marginale, prevention in cattle is… 
2012
2012
Sporozoite neutralizing antibodies elicited in mice and rhesus macaques immunized with a Plasmodium falciparum repeat peptide conjugated to meningococcal outer membrane protein complex
Antibodies that neutralize infectivity of malaria sporozoites target the central repeat region of the circumsporozoite (CS… 
2012
2012
ISCOMATRIX Application of Nanotechnology
Immunostimulatory complexes (ISCOMs), composed of antigen, saponin, cholesterol, and phospholipid, are the typical nano materials… 
2011
2011
Evaluating functional antibodies in rhesus monkeys immunized with hepatitis B virus surface antigen vaccine with novel adjuvant formulations.
2009
2009
Evaluation of vaccines for H 5 N 1 influenza virus in ferrets reveals the potential for 2 protective single-shot immunisation
Melbourne, Parkville, Victoria, Australia 4 . 11 12 13 14 15 16 *Corresponding author: Mailing address: Department of… 
2007
2007
ISS (ImmunoStimulatory Sequences) and Iscomatrix boost vaccine-generated HBV-specific immunity in mice (B202)
We have investigated the adjuvant activity of both CpG motif-containing ImmunoStimulatory Sequences (ISS) and the saponin… 
2006
2006
Phase II trial of vaccination with full length NY-ESO-1/IMX in patients with advanced malignant melanoma.
2571 Background: NY-ESO-1 is an immunogenic "cancer-testis" (CT) antigen, expressed in many cancers including melanoma… 
2004
2004
Association of antigens to ISCOMATRIX adjuvant using metal chelation leads to improved CTL responses.
Review
1997
Review
1997
Development of an Influenza-Iscom™ Vaccine
Annual immunisation of the elderly with trivalent influenza vaccines is an important public health measure (Mullooly et al, 1994… 
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