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ISCOMATRIX

 
National Institutes of Health

Papers overview

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Review
2012
Review
2012
The ISCOMATRIX adjuvant has antigen delivery and presentation properties as well as immunomodulatory capabilities, which combine… Expand
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Highly Cited
2012
Highly Cited
2012
Generating a cytotoxic CD8+ T-cell response that can eradicate malignant cells is the primary objective of cancer vaccine… Expand
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Highly Cited
2010
Highly Cited
2010
Truncated recombinant dengue virus envelope protein subunits (80E) are efficiently expressed using the Drosophila Schneider-2 (S2… Expand
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Review
2009
Review
2009
Adjuvants are components that when added to subunit antigen (Ag) vaccines boost their immunogenicity and thus immune efficacy… Expand
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Highly Cited
2009
Highly Cited
2009
Cancer vaccines aim to induce antitumor CTL responses, which require cross-presentation of tumor Ag to CTLs by dendritic cells… Expand
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Review
2007
Review
2007
The ISCOMATRIX™ adjuvant has antigen-delivery and -presentation properties, as well as immunomodulatory capabilities that combine… Expand
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Review
2005
Review
2005
The immunostimulating complex, referred to as 'iscom', was first described by Morein et al. in 1984 as a novel structure for… Expand
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Highly Cited
2005
Highly Cited
2005
Dendritic cells (DCs) are being evaluated for cancer immunotherapy due to their unique ability to induce tumor-directed T-cell… Expand
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Highly Cited
2004
Highly Cited
2004
NY-ESO-1 is a "cancer-testis" antigen expressed in many cancers. ISCOMATRIX is a saponin-based adjuvant that induces antibody and… Expand
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2004
2004
Human Papillomavirus type 16 (HPV16) E6 and E7 oncoproteins are associated with cervical cancer development and progression and… Expand
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