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National Institutes of Health
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In cancer cell lines inhibition of SCF/c-Kit pathway leads to radiosensitization only when SCF is strongly over-expressed
Florian H Leinberger
Florentine S. B. Subtil
Clinical and translational radiation oncology
Corpus ID: 4798686
Background and purpose The SCF/c-Kit pathway is often overexpressed in human tumors leading to an enhanced tumorigenesis…
Long noncoding RNA, CCDC26, controls myeloid leukemia cell growth through regulation of KIT expression
Corpus ID: 18737342
BackgroundAccumulating evidence suggests that some long noncoding RNAs (lncRNAs) are involved in certain diseases, such as cancer…
Comparison of the effects of carbon ion and photon irradiation on the angiogenic response in human lung adenocarcinoma cells.
International journal of radiation oncology…
Corpus ID: 20332359
PURPOSE Radiotherapy resistance is a commonly encountered problem in cancer treatment. In this regard, stabilization of…
[4-t-butylphenyl]-N-(4-imidazol-1-yl phenyl)sulfonamide (ISCK03) inhibits SCF/c-kit signaling in 501mel human melanoma cells and abolishes melanin production in mice and brownish guinea pigs.
Heung Su Baek
Soo Mi Ahn
H. J. Shin
J. S. Hwang
Corpus ID: 38501788
It is well known that c-kit is related to pigmentation as well as to the oncology target protein. The objective of this study was…
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