IRS1 wt Allele

Known as: HIRS-1, Insulin Receptor Substrate 1 wt Allele

Human IRS1 wild-type allele is located in the vicinity of 2q36 and is approximately 65 kb in length. This allele, which encodes insulin receptor…

National Institutes of Health

Papers overview

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2008

Aim: Insulin receptor substrate, type 1 (IRS‐1) transmits growth and survival signals, and is overexpressed in more than 90% of…