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IRF8 gene

Known as: ICSBP1, Interferon Regulatory Factor 8 Gene, INTERFERON REGULATORY FACTOR 8 
This gene plays a role in the regulation of cytokine gene expression.
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
Dendritic cells (DCs) are essential regulators of immune responses; however, transcriptional mechanisms that establish DC lineage… Expand
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Highly Cited
2011
Highly Cited
2011
BACKGROUND The genetic analysis of human primary immunodeficiencies has defined the contribution of specific cell populations and… Expand
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Highly Cited
2008
Highly Cited
2008
Among dendritic cell (DC) subsets, CD8alpha(+) DCs and plasmacytoid DCs (pDCs) produce high levels of IL12 and type I interferons… Expand
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Highly Cited
2008
Highly Cited
2008
The glucocorticoid receptor (GR) is phosphorylated at multiple sites within its N terminus (S203, S211, S226), yet the role of… Expand
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Highly Cited
2008
Highly Cited
2008
PU.1, IKAROS, E2A, EBF, and PAX5 comprise a transcriptional network that orchestrates B-cell lineage specification, commitment… Expand
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Highly Cited
2007
Highly Cited
2007
Promiscuous expression of tissue-restricted auto-antigens in the thymus imposes T-cell tolerance and provides protection from… Expand
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2007
2007
INTRODUCTION In studies of pharmacogenomics, it is essential to address gene-gene and gene-environment interactions to describe… Expand
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Highly Cited
2006
Highly Cited
2006
The Mediator subunits MED14 and MED1 have been implicated in transcriptional regulation by the glucocorticoid receptor (GR) by… Expand
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2006
2006
BACKGROUND A combination of interferon-alpha (IFN-alpha) and ribavirin has been the choice for treating chronic hepatitis C (CHC… Expand
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Highly Cited
2005
Highly Cited
2005
BXH-2 mice develop a fatal myeloid leukemia by a two-step mutagenic process. First, a BXH-2–specific recessive mutation causes a… Expand
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