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Interferon Regulatory Factor 8

Known as: ICS binding protein, IFN consensus sequence binding protein, H-ICSBP 
Interferon regulatory factor 8 (426 aa, ~48 kDa) is encoded by the human IRF8 gene. This protein plays a role in the regulation of gene transcription… 
National Institutes of Health

Related topics

Related topics

11 relations

Broader (2)

Carrier ProteinsInterferon Regulatory Factors
DNA-Binding ProteinsGenes, RegulatorIRF8 geneIRF8 wt Allele

Papers overview

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2013
2013
IRF5, IRF8, and IRF7 in human pDCs — the good, the bad, and the insignificant?
Interferon (IFN) regulatory factors (IRFs) are transcription factors with versatile functions in the regulation of innate and… 
2012
2012
Interferon Regulatory Factor-8 Is Important for Histone Deacetylase Inhibitor-Mediated Antitumor Activity
The notion that epigenetic alterations in neoplasia are reversible has provided the rationale to identify epigenetic modifiers… 
2011
2011
The plant limonoid 7-oxo-deacetoxygedunin inhibits RANKL-induced osteoclastogenesis by suppressing activation of the NF-κB and MAPK pathways.
Review
2010
Review
2010
A multi-functional role of interferon regulatory factor-8 in solid tumor and myeloid cell biology
Understanding mechanisms of tumor escape are critically important not only to improving our knowledge of cancer biology, but also… 
2002
2002
CpG DNA induced IL-12 p40 gene activation is independent of STAT1 activation or production of interferon consensus sequence binding protein.
The host immune system responds to CpG motifs in bacterial DNA by rapidly producing proinflammatory cytokines. The host response… 
2000
2000
Sequence comparison of avian interferon regulatory factors and identification of the avian CEC-32 cell as a quail cell line.
Interferon (IFN) regulatory factor-1 (IRF-1) is a well-characterized member of the IRF family. Previously, we have cloned cDNA of… 
1999
1999
Functional Analysis of Human Herpesvirus 8-Encoded Viral Interferon Regulatory Factor 1 and Its Association with Cellular Interferon Regulatory Factors and p 300
Human herpesvirus 8/Kaposi sarcoma-associated virus (HHV-8/KSHV) contains, in addition to genes required for viral replication, a… 
1998
1998
Analysis of the antagonist effect of IFN-alpha on IFN-gamma-induced interferon consensus sequence binding protein messenger RNA in murine macrophages.
Interferon consensus sequence binding protein (ICSBP), a member of the interferon regulatory factor family of DNA binding… 
1993
1993
Interleukin-6 activates and regulates transcription factors of the interferon regulatory factor family in M1 cells.
1990
1990
Transgenic Mice and Mutants in MHC Research
This volume contains papers presented at the international conference on "Transgenic Mice and Mutants in MHC Research," held in… 
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