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INCENP gene

Known as: FLJ31633, INCENP, INNER CENTROMERE PROTEIN 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Two mechanisms coordinate the recruitment of the chromosomal passenger complex to the plane of cell division
Proper positioning of the chromosomal passenger complex (CPC) at the cell division plane is required for cytokinesis. We show… 
2014
2014
Increased Aurora B activity causes continuous disruption of kinetochore–microtubule attachments and spindle instability
Significance During mitosis, Aurora B kinase plays a key role in ensuring that sister chromatids (each of the copies of a… 
Highly Cited
2011
Highly Cited
2011
Functional analysis of the microtubule-interacting transcriptome
A combination of bioinformatic and RNA interference analysis of Xenopus tropicalis RNA-seq data shows that the identification of… 
Highly Cited
2005
Highly Cited
2005
Overexpression of an Aurora-C kinase-deficient mutant disrupts the Aurora-B/INCENP complex and induces polyploidy.
Aurora kinases are emerging as key regulators of centrosome function, chromosome segregation and cytokinesis. We previously… 
Highly Cited
2004
Highly Cited
2004
Megakaryocytes express functional Aurora-B kinase in endomitosis.
Endomitosis (EnM) in megakaryocytes (MKs) is characterized by abortion of mitosis in late anaphase and failure of cytokinesis… 
Highly Cited
2002
Highly Cited
2002
Proteomic analysis of human metaphase chromosomes reveals topoisomerase II alpha as an Aurora B substrate.
The essential Aurora B kinase is a chromosomal passenger protein that is required for mitotic chromosome alignment and… 
Highly Cited
2001
Highly Cited
2001
INCENP binds directly to tubulin and requires dynamic microtubules to target to the cleavage furrow.
Inner centromere protein (INCENP) is a chromosomal passenger protein with an essential role in mitosis. At the metaphase/anaphase… 
Highly Cited
1999
Highly Cited
1999
Defective chromosome segregation, microtubule bundling and nuclear bridging in inner centromere protein gene (Incenp)-disrupted mice.
INCENP is a chromosomal passenger protein which relocates from the centromere to thel spindle midzone during the metaphase… 
Highly Cited
1999
Highly Cited
1999
Cleavage furrows formed between centrosomes lacking an intervening spindle and chromosomes contain microtubule bundles, INCENP, and CHO1 but not CENP-E.
PtK1 cells containing two independent mitotic spindles can cleave between neighboring centrosomes, in the absence of an… 
Highly Cited
1993
Highly Cited
1993
Molecular analysis of the INCENPs (inner centromere proteins): separate domains are required for association with microtubules during interphase and with the central spindle during anaphase
It has recently been proposed that mitotic chromosomes transport certain cytoskeletal proteins to the metaphase plate so that… 
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