FAQ

INCENP gene

Known as: FLJ31633, INCENP, INNER CENTROMERE PROTEIN 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1989-2017
051019892017

Papers overview

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Highly Cited
2006
Highly Cited
2006
Complex formation of Plk1 and INCENP required for metaphase–anaphase transition
Mitotic chromosomal dynamics is regulated by the coordinated activities of many mitotic kinases, such as cyclin-dependent kinase… (More)
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Highly Cited
2005
Highly Cited
2005
Mechanism of Aurora B activation by INCENP and inhibition by hesperadin.
Aurora family serine/threonine kinases control mitotic progression, and their deregulation is implicated in tumorigenesis. Aurora… (More)
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Highly Cited
2003
Highly Cited
2003
Exploring the functional interactions between Aurora B, INCENP, and survivin in mitosis.
The function of the Aurora B kinase at centromeres and the central spindle is crucial for chromosome segregation and cytokinesis… (More)
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Highly Cited
2003
Highly Cited
2003
Separase regulates INCENP-Aurora B anaphase spindle function through Cdc14.
The inner centromere-like protein (INCENP) forms a complex with the evolutionarily conserved family of Aurora Bkinases. The… (More)
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Highly Cited
2003
Highly Cited
2003
Condensin is required for nonhistone protein assembly and structural integrity of vertebrate mitotic chromosomes.
The dramatic condensation of chromosomes that occurs during mitosis is widely thought to be largely controlled by a protein… (More)
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Highly Cited
2002
Highly Cited
2002
Evidence that the Ipl1-Sli15 (Aurora Kinase-INCENP) Complex Promotes Chromosome Bi-orientation by Altering Kinetochore-Spindle Pole Connections
How sister kinetochores attach to microtubules from opposite spindle poles during mitosis (bi-orientation) remains poorly… (More)
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Highly Cited
2002
Highly Cited
2002
Aurora B kinase exists in a complex with survivin and INCENP and its kinase activity is stimulated by survivin binding and phosphorylation.
Aurora B regulates chromosome segregation and cytokinesis and is the first protein to be implicated as a regulator of bipolar… (More)
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Highly Cited
2001
Highly Cited
2001
Essential Roles of Drosophila Inner Centromere Protein (Incenp) and Aurora B in Histone H3 Phosphorylation, Metaphase Chromosome Alignment, Kinetochore Disjunction, and Chromosome Segregation
We have performed a biochemical and double-stranded RNA-mediated interference (RNAi) analysis of the role of two chromosomal… (More)
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Highly Cited
2000
Highly Cited
2000
Survivin and the inner centromere protein INCENP show similar cell-cycle localization and gene knockout phenotype
BACKGROUND Survivin is a mammalian protein that carries a motif typical of the inhibitor of apoptosis (IAP)proteins, first… (More)
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Highly Cited
2000
Highly Cited
2000
INCENP binds the Aurora-related kinase AIRK2 and is required to target it to chromosomes, the central spindle and cleavage furrow
Cytoskeletal rearrangements during mitosis must be co-ordinated with chromosome movements. The 'chromosomal passenger' proteins… (More)
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