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INCENP gene

Known as: FLJ31633, INCENP, INNER CENTROMERE PROTEIN 
 
National Institutes of Health

Papers overview

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Review
2012
Review
2012
The chromosomal passenger complex (CPC): from easy rider to the godfather of mitosis
Successful cell division requires the precise and timely coordination of chromosomal, cytoskeletal and membrane trafficking… Expand
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Highly Cited
2005
Highly Cited
2005
Mechanism of Aurora B activation by INCENP and inhibition by hesperadin.
Aurora family serine/threonine kinases control mitotic progression, and their deregulation is implicated in tumorigenesis. Aurora… Expand
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Highly Cited
2005
Highly Cited
2005
Complex formation of Plk1 and INCENP required for metaphase–anaphase transition
Mitotic chromosomal dynamics is regulated by the coordinated activities of many mitotic kinases, such as cyclin-dependent kinase… Expand
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Highly Cited
2004
Highly Cited
2004
Borealin: a novel chromosomal passenger required for stability of the bipolar mitotic spindle.
The chromosomal passenger complex of Aurora B kinase, INCENP, and Survivin has essential regulatory roles at centromeres and the… Expand
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Highly Cited
2003
Highly Cited
2003
Exploring the functional interactions between Aurora B, INCENP, and survivin in mitosis.
The function of the Aurora B kinase at centromeres and the central spindle is crucial for chromosome segregation and cytokinesis… Expand
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Highly Cited
2002
Highly Cited
2002
Phosphorylation of the Carboxyl Terminus of Inner Centromere Protein (INCENP) by the Aurora B Kinase Stimulates Aurora B Kinase Activity*
How the events of mitosis are coordinated is not well understood. Intriguing mitotic regulators include the chromosomal passenger… Expand
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Highly Cited
2001
Highly Cited
2001
Essential Roles of Drosophila Inner Centromere Protein (Incenp) and Aurora B in Histone H3 Phosphorylation, Metaphase Chromosome Alignment, Kinetochore Disjunction, and Chromosome Segregation
We have performed a biochemical and double-stranded RNA-mediated interference (RNAi) analysis of the role of two chromosomal… Expand
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Highly Cited
2000
Highly Cited
2000
Survivin and the inner centromere protein INCENP show similar cell-cycle localization and gene knockout phenotype
BACKGROUND Survivin is a mammalian protein that carries a motif typical of the inhibitor of apoptosis (IAP)proteins, first… Expand
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Highly Cited
2000
Highly Cited
2000
INCENP binds the Aurora-related kinase AIRK2 and is required to target it to chromosomes, the central spindle and cleavage furrow
Cytoskeletal rearrangements during mitosis must be co-ordinated with chromosome movements. The 'chromosomal passenger' proteins… Expand
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Highly Cited
1998
Highly Cited
1998
INCENP Centromere and Spindle Targeting: Identification of Essential Conserved Motifs and Involvement of Heterochromatin Protein HP1
The inner centromere protein (INCENP) has a modular organization, with domains required for chromosomal and cytoskeletal… Expand
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