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INC280

Known as: INCB028060 
 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
9004Background: Capmatinib is a highly potent and selective MET inhibitor. Previous data of GEOMETRY mono-1 study showed a… Expand
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2018
2018
PURPOSE MET dysregulation occurs in up to 26% of non-small-cell lung cancers (NSCLCs) after epidermal growth factor receptor… Expand
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2016
2016
9020Background: Most pts withEGFR-mut NSCLC progress on EGFR tyrosine kinase inhibitor (TKI) therapy despite high initial… Expand
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2016
2016
9067Background: cMET dysregulation occurs in 3–10% of NSCLC and is a negative prognostic factor. INC280 is a highly selective… Expand
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2016
2016
Non-small cell lung cancer patients carrying oncogenic EGFR mutations initially respond to EGFR-targeted therapy, but later… Expand
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2015
2015
BackgroundExpression and activation of the cMET receptor have been implicated in tumor progression and resistance to chemotherapy… Expand
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2015
2015
5-year survival rates for ovarian cancer are approximately 40%, and for women diagnosed at late stage (the majority), just 27… Expand
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2014
2014
2520^ Background: Aberrations in the MET receptor tyrosine kinase pathway occur in various human malignancies (via MET… Expand
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2014
2014
8017 Background: Despite high response rates to EGFR tyrosine kinase inhibitors (TKIs), most patients (pts) with EGFR-mut NSCLC… Expand
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2014
2014
BackgroundEpithelioid sarcoma (EpS) is a high-grade malignant soft-tissue sarcoma characterized by local recurrences and distant… Expand
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