Skip to search formSkip to main contentSkip to account menu

IMD 0354

Known as: IMD-0354, IMD0354 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
4-Hydroxy-N-[3,5-bis(trifluoromethyl)phenyl]-1,2,5-thiadiazole-3-carboxamide: a novel inhibitor of the canonical NF-κB cascade.
The NF-κB signaling pathway is a validated oncological target. Here, we applied scaffold hopping to IMD-0354, a presumed IKK… 
2015
2015
IKK inhibition prevents PM2.5-exacerbated cardiac injury in mice with type 2 diabetes.
2014
2014
IκB kinase-β inhibitor IMD-0354 beneficially suppresses retinal vascular permeability in streptozotocin-induced diabetic mice.
PURPOSE The purpose of the present study is to evaluate the effect of selective IKK-β inhibition by IMD-0354 on inflammation… 
Highly Cited
2013
Highly Cited
2013
IMD-0354 Targets Breast Cancer Stem Cells: A Novel Approach for an Adjuvant to Chemotherapy to Prevent Multidrug Resistance in a Murine Model
Although early detection of breast cancer improved in recent years, prognosis of patients with late stage breast cancer remains… 
2012
2012
Activation of nuclear factor-κB pathway is responsible for tumor necrosis factor-α-induced up-regulation of endothelin B2 receptor expression in vascular smooth muscle cells in vitro.
2012
2012
Amelioration of endotoxin-induced uveitis treated with an IκB kinase β inhibitor in rats
Purpose Endotoxin-induced uveitis (EIU) is an animal model for acute ocular inflammation. Several substances play major roles in… 
2010
2010
NF-kappaB signaling mediates vascular smooth muscle endothelin type B receptor expression in resistance arteries.
Highly Cited
2007
Highly Cited
2007
Thymic stromal lymphopoietin secretion of synovial fibroblasts is positively and negatively regulated by Toll-like receptors/nuclear factor-κB pathway and interferon-γ/dexamethasone
Thymic stromal lymphopoietin (TSLP) is an interleukin (IL)-7-like cytokine produced by epithelial cells and triggers dendritic… 
2007
2007
Inhibition of NF-{kappa}B improves left ventricular remodeling and cardiac dysfunction after myocardial infarction.
Several studies have demonstrated that NF-kappaB is substantially involved in the progression of cardiac remodeling; however, it… 
2007
2007
Thymic stromal lymphopoietin secretion of synovial fibroblasts is positively and negatively regulated by Toll-like receptors/nuclear factor-kappaB pathway and interferon-gamma/dexamethasone.
Thymic stromal lymphopoietin (TSLP) is an interleukin (IL)-7-like cytokine produced by epithelial cells and triggers dendritic… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)