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IL33 protein, human

Known as: chromosome 9 open reading frame 26 protein, human, NF-HEV, C9orf26 protein, human 
Interleukin-33 (270 aa, ~31 kDa) is encoded by the human IL33 gene. This protein plays a role in the positive regulation of inflammation.
National Institutes of Health

Related topics

Related topics

13 relations
Cell Proliferation Regulatory ProcessCytokine GeneCytokine Receptor BindingCytokine Signaling

Broader (1)

Interleukin-33

Papers overview

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Highly Cited
2013
Highly Cited
2013
Severe obesity increases adipose tissue expression of interleukin-33 and its receptor ST2, both predominantly detectable in endothelial cells of human adipose tissue
Objective:Obesity is associated with chronic inflammation of the adipose tissue, which contributes to obesity-associated… 
Review
2012
Review
2012
Danger Signals Activating the Immune Response after Trauma
Sterile injury can cause a systemic inflammatory response syndrome (SIRS) that resembles the host response during sepsis. The… 
Highly Cited
2010
Highly Cited
2010
Interleukin-33 attenuates sepsis by enhancing neutrophil influx to the site of infection
Sepsis is a systemic inflammatory condition following bacterial infection with a high mortality rate and limited therapeutic… 
Highly Cited
2010
Highly Cited
2010
Inflammatory bowel disease-associated interleukin-33 is preferentially expressed in ulceration-associated myofibroblasts.
Interleukin-33 (IL-33) is a novel member of the interleukin-1 family that induces mucosal pathology in vivo and may drive… 
Highly Cited
2009
Highly Cited
2009
Inhibition of interleukin-33 signaling attenuates the severity of experimental arthritis.
OBJECTIVE Interleukin-33 (IL-33; or, IL-1F11) was recently identified as the ligand of the IL-1 family receptor T1/ST2. The aim… 
Highly Cited
2009
Highly Cited
2009
Developing multiplexed assays for troponin I and interleukin-33 in plasma by peptide immunoaffinity enrichment and targeted mass spectrometry.
BACKGROUND Protein biomarker candidates from discovery proteomics must be quantitatively verified in patient samples before they… 
Highly Cited
2008
Highly Cited
2008
IL-33, a Potent Inducer of Adaptive Immunity to Intestinal Nematodes1
IL-33 (IL-1F11) binds ST2 (IL-1R4), both of which are associated with optimal CD4+ Th2 polarization. Exogenous IL-33 drives… 
Highly Cited
2008
Highly Cited
2008
Association of serum interleukin‐33 level and the interleukin‐33 genetic variant with Japanese cedar pollinosis
Background IL‐33, an IL‐1‐like cytokine, is a ligand for IL1RL1, which is an important effector molecule of type 2 T helper… 
Highly Cited
2008
Highly Cited
2008
Interleukin-33 enhances adhesion, CD11b expression and survival in human eosinophils
Eosinophils are important effector cells in allergic diseases, but the mechanisms regulating their biological functions remain… 
Highly Cited
2007
Highly Cited
2007
Interleukin (IL)-33 induces the release of pro-inflammatory mediators by mast cells.
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