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IL32 wt Allele

Known as: TAIF, Natural Killer Cell Transcript 4 Gene, Interleukin 32 wt Allele 
Human IL32 wild-type allele is located in the vicinity of 16p13.3 and is approximately 17 kb in length. This allele, which encodes interleukin-32… 
National Institutes of Health

Related topics

Related topics

8 relations
16p13.3Cell Proliferation Regulatory ProcessCytokine Receptor BindingCytokine Signaling

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2009
Highly Cited
2009
IL-32–dependent effects of IL-1β on endothelial cell functions
Increasing evidence demonstrates that interleukin (IL)–32 is a pro-inflammatory cytokine, inducing IL-1α, IL-1β, IL-6, tumor… 
Highly Cited
2007
Highly Cited
2007
Targeted delivery of NK4 to multiple lung tumors by bone marrow-derived mesenchymal stem cells
Most advanced solid tumors metastasize to different organs. However, no gene therapy effective for multiple tumors has yet been… 
Highly Cited
2007
Highly Cited
2007
Epithelial overexpression of interleukin-32alpha in inflammatory bowel disease.
Interleukin (IL)-32 is a recently described proinflammatory cytokine, characterized by induction of nuclear factor (NF)-kappaB… 
Highly Cited
2006
Highly Cited
2006
Proteinase 3 is an IL-32 binding protein.
IL-32, a recently discovered proinflammatory cytokine with four isoforms, induces IL-1beta, TNF-alpha, IL-6, and chemokines. Here… 
Highly Cited
2005
Highly Cited
2005
Identification of metastasis-associated genes in prostate cancer by genetic profiling of human prostate cancer cell lines.
OBJECTIVES Prostate cancer (PCa) is a heterogeneous tumour entity with known interindividual differences in biological behaviour… 
Highly Cited
2002
Highly Cited
2002
Targeting angiogenesis and HGF function using an adenoviral vector expressing the HGF antagonist NK4 for cancer therapy.
Hepatocyte growth factor (HGF) affects tumor growth/invasion and tumor neovascularization. A proposed HGF antagonist, NK4 (an… 
Highly Cited
2001
Highly Cited
2001
NK4, a four-kringle antagonist of HGF, inhibits spreading and invasion of human pancreatic cancer cells
Because of the highly aggressive behaviour, i.e. invasive, disseminative and metastatic properties, the outcome for patients with… 
Highly Cited
2000
Highly Cited
2000
HGF/NK4, a four-kringle antagonist of hepatocyte growth factor, is an angiogenesis inhibitor that suppresses tumor growth and metastasis in mice.
We reported that NK4, composed of the N-terminal hairpin and subsequent four kringle domains of hepatocyte growth factor (HGF… 
Highly Cited
2000
Highly Cited
2000
Nk4, a new HGF/SF variant, is an antagonist to the influence of HGF/SF on the motility and invasion of colon cancer cells
Hepatocyte Growth Factor/Scatter Factor (HGF/SF) is a heterodimeric molecule that plays a key role in the regulation of migration… 
Highly Cited
1999
Highly Cited
1999
Antagonistic effect of NK4, a novel hepatocyte growth factor variant, on in vitro angiogenesis of human vascular endothelial cells.
Hepatocyte growth factor (HGF), also known as scatter factor (SF), is known to act on cancer cells as well as endothelial cells… 
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