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IL1RL1 protein, human

Known as: FIT-1 protein, human, ST2 protein, human, IL1RL1 
Interleukin-1 receptor-like 1 (556 aa, ~63 kDa) is encoded by the human IL1RL1 gene. This protein plays a role in binding interleukin-33 and immune… 
National Institutes of Health

Related topics

Related topics

14 relations
Cytokine Receptor GeneCytokine Signaling ProcessIL1RL1 geneImmunoglobulin C2-set Domain

Broader (1)

Interleukin-1 Receptor-Like 1 Protein

Papers overview

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Highly Cited
2018
Highly Cited
2018
Pulmonary Production of Soluble ST2 in Heart Failure
Background: Serum concentrations of ST2 (interleukin-1 receptor-like 1) represent a meaningful prognostic marker in cardiac… 
Highly Cited
2015
Highly Cited
2015
Transcription factor Hes1 modulates osteoarthritis development in cooperation with calcium/calmodulin-dependent protein kinase 2
Significance Here we demonstrate that Hes1, an important target of Notch signaling, modulated pathogenesis of osteoarthritis by… 
Highly Cited
2015
Highly Cited
2015
IL-33 Receptor ST2 Amplifies the Expansion of NK Cells and Enhances Host Defense during Mouse Cytomegalovirus Infection
NK cells provide important host defense against viruses and can differentiate into self-renewing memory NK cells after infection… 
Highly Cited
2015
Highly Cited
2015
Phenotypic and genotypic association of epithelial IL1RL1 to human TH2-like asthma.
Highly Cited
2014
Highly Cited
2014
IL-33 and Thymic Stromal Lymphopoietin Mediate Immune Pathology in Response to Chronic Airborne Allergen Exposure
Humans are frequently exposed to various airborne allergens in the atmospheric environment. These allergens may trigger a complex… 
Highly Cited
2013
Highly Cited
2013
Specification of type 2 innate lymphocytes by the transcriptional determinant Gfi1
Type 2 innate lymphoid cells (ILC2 cells) participate in host defense against helminth parasites and in allergic inflammation… 
Highly Cited
2013
Highly Cited
2013
Common genetic variation at the IL1RL1 locus regulates IL-33/ST2 signaling.
The suppression of tumorigenicity 2/IL-33 (ST2/IL-33) pathway has been implicated in several immune and inflammatory diseases… 
2012
2012
Effects of interleukin-33 on cardiac fibroblast gene expression and activity.
Highly Cited
2011
Highly Cited
2011
Interleukin-1 receptor-like 1 polymorphisms are associated with serum IL1RL1-a, eosinophils, and asthma in childhood.
Highly Cited
2008
Highly Cited
2008
Association of serum interleukin‐33 level and the interleukin‐33 genetic variant with Japanese cedar pollinosis
Background IL‐33, an IL‐1‐like cytokine, is a ligand for IL1RL1, which is an important effector molecule of type 2 T helper… 
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