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IL18BP protein, human

Known as: IL-18BP, IL-18BP protein, human, MC51L-53L-54L Homolog Gene Product 
Interleukin-18-binding protein (194 aa, ~21 kDa) is encoded by the human IL18BP gene. This protein plays a role in binding to and sequestration of… 
National Institutes of Health

Related topics

Related topics

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Extracellular SpaceGenes, RegulatorIL18BP geneImmunoglobulin C2-set Domain

Broader (1)

interleukin-18 binding protein

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
The IL-18 Antagonist IL-18–Binding Protein Is Produced in the Human Ovarian Cancer Microenvironment
Purpose: Interleukin (IL)-18 is an immune-enhancing cytokine, which induces IFN-γ production, T-helper 1 responses, and antitumor… 
2012
2012
IL-27 Regulates IL-18 Binding Protein in Skin Resident Cells
IL-18 is an important mediator involved in chronic inflammatory conditions such as cutaneous lupus erythematosus, psoriasis and… 
2012
2012
Relationship between inflammatory mediators, Aβ levels and ApoE genotype in Alzheimer disease.
Activation of inflammatory processes is observed within the brain as well as periphery of subjects with Alzheimer's disease (AD… 
2011
2011
Immunomodulatory IL‐18 binding protein is produced by prostate cancer cells and its levels in urine and serum correlate with tumor status
Cytokines may play a role in the initiation and progression of prostate cancer. A cytokine antibody array was previously applied… 
2006
2006
Interleukin‐18 Affects Local Cytokine Expression But Does Not Impact on the Development of Kidney Allograft Rejection
Interleukin‐18 is predominantly a macrophage‐derived cytokine with a key role in inflammation and cell‐mediated immunity. Having… 
2003
2003
A Switch to High-Flux Helixone® Membranes Reverses Suppressed Interferon-γ Production in Patients on Low-Flux Dialysis
Long-term hemodialysis (HD) induces an inflammatory response and is associated with a suppressed cellular immune response… 
Highly Cited
2003
Highly Cited
2003
Interleukin-18, interleukin-18 binding protein and impaired production of interferon-gamma in chronic renal failure.
UNLABELLED Uremia is associated with suppressed cellular immune responses, manifested, in part, by impaired interferon-gamma… 
Highly Cited
2002
Highly Cited
2002
Interleukin-18/Interleukin-18 Binding Protein Signaling Modulates Ischemia-Induced Neovascularization in Mice Hindlimb
Abstract— Identification of factors that may stimulate ischemia-induced neovascularization without increasing atherosclerotic… 
2002
2002
The promoter of IL-18 binding protein: activation by an IFN-gamma -induced complex of IFN regulatory factor 1 and CCAAT/enhancer binding protein beta.
The IL-18 binding protein (IL-18BP) is a circulating inhibitor of the proinflammatory cytokine IL-18. It is constitutively… 
2001
2001
Differential Roles of Interleukin-18 (IL-18) and IL-12 for Induction of Gamma Interferon by Staphylococcal Cell Wall Components and Superantigens
ABSTRACT The roles of endogenous cytokines induced by either intact staphylococcal microorganisms or staphylococcal exotoxins… 
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