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IL17A protein, human

Known as: Interleukin-17, Cytotoxic T-Lymphocyte-Associated Antigen 8, IL-17A, human 
Interleukin-17A (155 aa, ~18 kDa) is encoded by the human IL17A gene. This protein is involved in the positive regulation of cytokine production.
National Institutes of Health

Related topics

Related topics

16 relations
Cell Proliferation Regulatory ProcessCytokine GeneCytokine Receptor BindingCytokine Signaling

Broader (2)

Interleukin-17Interleukin-17A

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
IL-17A-producing T cells are associated with the progression of lung adenocarcinoma
Accumulating evidence has shown that T cells are crucial in shaping the tumor microenvironment and regulating tumor development… 
2013
2013
Comparison of Interleukin-17- Producing Cells in Different Clinical Types of Alopecia Areata
T helper 17 cells, characterized by interleukin-17 (IL-17) production, play a critical role in the pathogenesis of autoimmune… 
Highly Cited
2012
Highly Cited
2012
The Adjuvant Double Mutant Escherichia coli Heat Labile Toxin Enhances IL-17A Production in Human T Cells Specific for Bacterial Vaccine Antigens
The strong adjuvant activity and low enterotoxicity of the novel mucosal adjuvant double mutant Escherichia coli heat labile… 
2011
2011
IL-23R rs11209026 polymorphism modulates IL-17A expression in patients with rheumatoid arthritis
The interleukin (IL)-17/IL-23 axis is an important pro-inflammatory pathway in rheumatoid arthritis (RA). IL-23 maintains CD4+ T… 
2011
2011
Interleukin-4 (IL-4) and IL-13 Suppress Excessive Neutrophil Infiltration and Hepatocyte Damage during Acute Murine Schistosomiasis Japonica
ABSTRACT Due to the importance of neutrophils and proinflammatory cytokines in schistosomal liver damage, we analyzed the… 
2009
2009
Cytokines differentially regulate CXCL10 production by interferon-gamma-stimulated or tumor necrosis factor-alpha-stimulated human gingival fibroblasts.
BACKGROUND AND OBJECTIVE CXC chemokine 10 (CXCL10) activates CXC chemokine receptor 3 (CXCR3) and attracts activated T-helper 1… 
2009
2009
Catechins Inhibit CCL20 Production in IL-17A-Stimulated Human Gingival Fibroblasts
CC chemokine ligand 20 (CCL20) plays a pivotal role in the recruitment of Th17 cells and thus in the development of periodontal… 
Highly Cited
2008
Highly Cited
2008
Pravastatin attenuates allergic airway inflammation by suppressing antigen sensitisation, interleukin 17 production and antigen presentation in the lung
Background: Statins are widely used to treat hyperlipidaemia. Their immunosuppressive effect has recently been confirmed in… 
Review
2006
Review
2006
Rationale and safety of anti-interleukin-23 and anti-interleukin-17A therapy
Purpose of review Interleukin-12 is a heterodimeric cytokine and an important mediator of the cellular immune response. The… 
Highly Cited
2006
Highly Cited
2006
IL-17A promotes the growth of airway epithelial cells through ERK-dependent signaling pathway.
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