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IL12B gene

Known as: CYTOTOXIC LYMPHOCYTE MATURATION FACTOR 2, NKSF2, CLMF 
This gene is involved in immunity/defense via the stimulation of both T cells and natural killer cells. It also plays a role in cell differentiation.
National Institutes of Health

Related topics

Related topics

18 relations
AsthmaCell Differentiation processCell Proliferation Regulatory ProcessCellular Immunity

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IL12B wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Increased expression of IL12B mRNA transcribed from the risk haplotype for Crohn’s disease is a risk factor for disease relapse in Japanese patients
BackgroundIL12B is a promising candidate for a susceptibility gene in Crohn’s disease (CD). The aim of this study was to perform… 
Review
2016
Review
2016
Update on the association between interleukin-12 p40 gene polymorphism and risk of psoriasis: A meta-analysis
2012
2012
Association of polymorphisms of cytokine and TLR-2 genes with long-term immunity to hepatitis B in children vaccinated early in life.
2012
2012
Interactions of interleukin-12A and interleukin-12B polymorphisms on the risk of intracranial aneurysm
Several lines of evidence indicate that inflammatory processes play pivotal role in the development of intracranial aneurysm (IA… 
2011
2011
Functional Inflammatory Genotypes in Ischemic Stroke: Could We Use Them to Predict Age of Onset and Long-Term Outcome?
Functional single-nucleotide polymorphisms (SNPs) of inflammatory cytokines have been previously related to the occurrence of an… 
2011
2011
Functional polymorphism in IL12B promoter site is associated with ulcerative colitis.
Ulcerative colitis (UC) is one of the two subtypes of inflammatory bowel disease (IBD). UC is a complex genetic disease that… 
2009
2009
Relationship between the IL-12B promoter polymorphism and allergic rhinitis, familial asthma, serum total IgE, and eosinophil level in asthma patients.
BACKGROUND IL-12B is a strong candidate gene for asthma. OBJECTIVES We investigated the relationship between IL-12B and asthma… 
2008
2008
IL12B polymorphisms are linked but not associated with Plasmodium falciparum parasitemia: a familial study in Burkina Faso
Chromosome 5q31–q33 has been linked to Plasmodium falciparum parasitemia in several independent studies. This chromosomal region… 
2007
2007
Association analysis of IL-12B and IL-23R polymorphisms in myocardial infarction
The notion that coronary atherosclerosis and its most severe phenotype, myocardial infarction (MI), are chronic inflammatory… 
2001
2001
The polymorphism in the 3′ untranslated region of IL12B has a negligible effect on the susceptibility to develop type 1 diabetes in Norway
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