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IL12B wt Allele

Known as: Interleukin 12B (Natural Killer Cell Stimulatory Factor 2, Cytotoxic Lymphocyte Maturation Factor 2, P40) Gene, IL-12B, CLMF 
Human IL12B wild-type allele is located within 5q31.1-q33.1 and is approximately 16 kb in length. This allele, which encodes interleukin-12 beta… 
National Institutes of Health

Related topics

Related topics

20 relations
5q31.1-q33.1AsthmaCell Differentiation processCell Proliferation Regulatory Process

Broader (1)

IL12B gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Association of IL-12Bpro polymorphism with tumor-infiltrating dendritic cells in colorectal cancer.
PURPOSE Chronic inflammation is a key component in the development and progression of colorectal cancer (CRC). A notable hallmark… 
2016
2016
AB0001 Genetic Variants in IL-12B and IL-27 in The Patients with Systemic Lupus Erythematosus
Background Type-1 immunity plays a fundamental pathogenic role in various diseases including systemic lupus erythematosus (SLE… 
2016
2016
The role of Cryptococcus laurentii and mycorrhizal fungi in the nutritional physiology of Lupinus angustifolius L. hosting N2-fixing nodules
The benefits of biological nitrogen fixation (BNF) for blue lupin (Lupinus angustifolius L.) are well known. However, it is… 
2015
2015
Interleukin-18, interleukin-12B and interferon-γ gene polymorphisms in Brazilian patients with rheumatoid arthritis: a pilot study.
Polymorphisms in interleukin (IL)-18, IL-12 and interferon (IFN)-γ genes are associated with different levels of cytokines… 
2012
2012
Genetic variation of IL-12 B ( + 1188 region ) is associated with its decreased circulating levels and susceptibility to type 2 diabetes : a study on south-eastern Iranian diabetic patients
Background: Type 2 Diabetes Mellitus (DM) is one of the most common types of endocrine disease and the immune system plays a… 
2011
2011
Disease Severity of Ankylosing Spondylitis Association of IL-12 B Genetic Polymorphism with the Susceptibility and 1
Objective. Interleukin 23 (IL-23) stimulates the differentiation of T helper 17 (Th17) cells, which are involved in the… 
2010
2010
Anti-Inflammatory Markers Are Associated with Glomerular Filtration Rate In Adults with Sickle Cell Disease.
Abstract 1652 Sickle cell disease (SCD) is characterized by increased systemic inflammation. Further, in a significant number of… 
2009
2009
IL-12B mRNA在儿童及青少年Hp相关性胃十二指肠疾病中的表达
目的研究白细胞介素12B(IL-12B)mRNA在儿童及青少年幽门螺杆菌(Hp)相关性胃十二指肠疾病胃黏膜中的表达。方法采用RT-PCR方法检测胃黏膜IL-12B mRNA表达。血清Hp-IgG抗体检测、PCR、尿素酶实验及组织学检查作为确定Hp… 
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