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IL10RB protein, human

Known as: CRF2-4 cytokine receptor, human, CRF2-4, Interleukin 10 Receptor Beta 
Interleukin-10 receptor subunit beta (325 aa, ~37 kDa) is encoded by the human IL10RB gene. This protein plays a role in cytokine signaling.
National Institutes of Health

Related topics

Related topics

15 relations
Cytokine Receptor GeneCytokine Signaling ProcessIL10RB geneImmune response

Broader (1)

Interleukin-10 Receptor beta Subunit

Papers overview

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Highly Cited
2014
Highly Cited
2014
Anti-Fibrotic Actions of Interleukin-10 against Hypertrophic Scarring by Activation of PI3K/AKT and STAT3 Signaling Pathways in Scar-Forming Fibroblasts
Background The hypertrophic scar (HS) is a serious fibrotic skin condition and a major clinical problem. Interleukin-10 (IL-10… 
Highly Cited
2012
Highly Cited
2012
A Regulatory Role for IL-10 Receptor Signaling in Development and B Cell Help of T Follicular Helper Cells in Mice
IL -10 is widely accepted as a survival, proliferation, and differentiation factor for B cells. However, IL-10 deficiency… 
2012
2012
Expression of the interleukin-10 signaling pathway genes in individuals with Down syndrome and periodontitis.
BACKGROUND Individuals with Down syndrome (DS) have a higher prevalence and severity of periodontal disease, which cannot be… 
2009
2009
Association study of IFNAR2 and IL10RB genes with the susceptibility and interferon response in HBV infection
Summary.  A recent genome‐wide association study discovered that two polymorphisms, interferon (IFN) alpha receptor 2 (IFNAR‐2… 
2007
2007
Positive replication and linkage disequilibrium mapping of the chromosome 21q22.1 malaria susceptibility locus
Four cytokine receptor genes are located on Chr21q22.11, encoding the α and β subunits of the interferon-α receptor (IFNAR1 and… 
Highly Cited
2006
Highly Cited
2006
Class II cytokine receptor gene cluster is a major locus for hepatitis B persistence.
Persistent hepatitis B virus infection is a major risk factor for hepatocellular carcinoma, the most frequent cancer in some… 
Review
2004
Review
2004
IL-22, a Th1 cytokine that targets the pancreas and select other peripheral tissues.
Highly Cited
2002
Highly Cited
2002
Interleukin-22 (IL-22) Activates the JAK/STAT, ERK, JNK, and p38 MAP Kinase Pathways in a Rat Hepatoma Cell Line
IL (interleukin)-22 is an IL-10-related cytokine; its main biological activity known thus far is the induction of acute phase… 
2002
2002
IL-10 receptor and coreceptor expression in quiescent and activated hepatic stellate cells.
Interleukin (IL)-10 expression is induced in activated hepatic stellate cells (HSC) in vitro and in vivo. We analyzed expression… 
Highly Cited
1993
Highly Cited
1993
A new member of the cytokine receptor gene family maps on chromosome 21 at less than 35 kb from IFNAR.
A full-length cDNA corresponding to a gene mapping to the D21S58 locus was cloned. The encoded protein, called CRF2-4, was shown… 
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