IKZF3 gene

Known as: IKZF3, AIO, IKAROS FAMILY ZINC FINGER 3 
This gene plays a role in both transcription in hematopoietic cells and lymphocyte development.
National Institutes of Health

Papers overview

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Highly Cited
2015
Highly Cited
2015
Which genetic alterations drive tumorigenesis and how they evolve over the course of disease and therapy are central questions in… (More)
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Highly Cited
2014
Highly Cited
2014
Lenalidomide is a drug with clinical efficacy in multiple myeloma and other B cell neoplasms, but its mechanism of action is… (More)
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Highly Cited
2014
Highly Cited
2014
Thalidomide-like drugs such as lenalidomide are clinically important treatments for multiple myeloma and show promise for other B… (More)
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Highly Cited
2010
Highly Cited
2010
Until recently, chromosomal translocations and fusion genes have been an underappreciated class of mutations in solid tumors… (More)
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Highly Cited
2010
Highly Cited
2010
Background:Cetuximab enhances the efficacy of chemotherapy in several cancer types. This trial assessed the activity of cetuximab… (More)
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Highly Cited
2007
Highly Cited
2007
Chromosomal aberrations are a hallmark of acute lymphoblastic leukaemia (ALL) but alone fail to induce leukaemia. To identify… (More)
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Highly Cited
2005
Highly Cited
2005
PURPOSE To demonstrate that adding irinotecan to a standard weekly schedule of high-dose, infusional fluorouracil (FU) and… (More)
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Highly Cited
2000
Highly Cited
2000
We have previously shown that Ikaros can repress transcription through the recruitment of histone deacetylase complexes. Here we… (More)
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Highly Cited
1999
Highly Cited
1999
The Ikaros gene family encodes zinc finger DNA-binding proteins essential for lineage determination and control of proliferation… (More)
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Highly Cited
1998
Highly Cited
1998
BACKGROUND Normal hematopoietic development depends on the activity of the Ikaros transcription factor, which contains distinct… (More)
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