IKZF3 wt Allele

Known as: Zinc Finger Protein, Subfamily 1A, 3 (Aiolos) Gene, AIO, AIOLOS 
Human IKZF3 wild-type allele is located in the vicinity of 17q21 and is approximately 99 kb in length. This allele, which encodes zinc finger protein… (More)
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
The genetic basis of hypodiploid acute lymphoblastic leukemia (ALL), a subtype of ALL characterized by aneuploidy and poor… (More)
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Highly Cited
2012
Highly Cited
2012
CD4+ interleukin 17 (IL-17)-producing helper T cells (TH17 cells) are instrumental in the immune response to pathogens. However… (More)
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Highly Cited
2010
Highly Cited
2010
Pre-B-cell expansion is driven by signals from the interleukin-7 receptor and the pre-B-cell receptor and is dependent on cyclin… (More)
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Highly Cited
2007
Highly Cited
2007
Chromosomal aberrations are a hallmark of acute lymphoblastic leukaemia (ALL) but alone fail to induce leukaemia. To identify… (More)
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Review
2003
Review
2003
Ikaros, Aiolos and Helios encode zinc finger transcription factors that are important regulators of lymphoid development and… (More)
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Highly Cited
2000
Highly Cited
2000
Gene targeting studies in mice have shown that the transcription factor Ikaros plays an essential role in lymphoid development… (More)
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Highly Cited
1999
Highly Cited
1999
Here we show that the lymphoid lineage-determining factors Ikaros and Aiolos can function as strong transcriptional repressors… (More)
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Highly Cited
1998
Highly Cited
1998
BACKGROUND Normal hematopoietic development depends on the activity of the Ikaros transcription factor, which contains distinct… (More)
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Highly Cited
1997
Highly Cited
1997
Development of the lymphoid system is dependent on the activity of zinc finger transcription factors encoded by the Ikaros gene… (More)
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Review
1997
Review
1997
The Ikaros gene, which encodes a family of hemopoietic-specific zinc finger proteins, is described as a central regulator of… (More)
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