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IFNAR2 gene

Known as: interferon alpha and beta receptor subunit 2, Interferon (Alpha, Beta and Omega) Receptor 2 Gene, IFNAR2 
This gene is involved in tyrosine-kinase signal transduction that elicits signaling events in the Jak/Stat and IRS pathways.
National Institutes of Health

Related topics

Related topics

8 relations
Antiviral ResponseCytokine Signaling ProcessIFNAR2 protein, humanIntercellular Communication Process

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2012
2012
Structural insights into a human anti-IFN antibody exerting therapeutic potential for systemic lupus erythematosus
Increasing evidences suggest that the type I interferon α (IFNα) plays a critical role in the etiopathogenesis of systemic lupus… 
2011
2011
Genetic variation in IL28RA is associated with the outcomes of HCV infection in a high-risk Chinese population.
Highly Cited
2009
Highly Cited
2009
Genetic Susceptibility to Respiratory Syncytial Virus Bronchiolitis in Preterm Children Is Associated With Airway Remodeling Genes and Innate Immune Genes
Prematurity is a risk factor for severe respiratory syncytial virus bronchiolitis. We show that genetic factors in innate immune… 
Highly Cited
2008
Highly Cited
2008
Photopatterned surfaces for site-specific and functional immobilization of proteins.
Photosensitive silanes containing nitroveratryl (Nvoc)-caged amine groups and protein repellent tetraethylene glycol units were… 
2007
2007
Comparable potency of IFNalpha2 and IFNbeta on immediate JAK/STAT activation but differential down-regulation of IFNAR2.
Type I IFNs (interferons) (IFNalpha/beta) form a family of related cytokines that control a variety of cellular functions through… 
2007
2007
Interferon receptor expression in multiple sclerosis patients
2004
2004
Initial expression of interferon alpha receptor 2 (IFNAR2) on CD34‐positive cells and its down‐regulation correlate with clinical response to interferon therapy in chronic myelogenous leukemia
Abstract:  In order to investigate the mechanism of interferon‐α (IFNα) action in the treatment of chronic myelogenous leukemia… 
2004
2004
Type I interferon receptor and response to interferon therapy in chronic hepatitis C patients: a prospective study
Summary.  The type I interferon (IFN) receptor consists of at least two subunits, IFNAR1 and IFNAR2. We previously found a… 
1999
1999
Characterization of a soluble ternary complex formed between human interferon‐β‐1a and its receptor chains
The extracellular portions of the chains that comprise the human type I interferon receptor, IFNAR1 and IFNAR2, have been… 
Highly Cited
1997
Highly Cited
1997
Molecular cloning of ovine and bovine type I interferon receptor subunits from uteri, and endometrial expression of messenger ribonucleic acid for ovine receptors during the estrous cycle and…
Interferon-tau (IFN-tau), a type I IFN structurally related to IFN-alpha, is regarded as the major antiluteolytic factor secreted… 
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