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IEM 1460

Known as: IEM-1460 
National Institutes of Health

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2 relations

Broader (1)

Adamantane
analogs & derivatives

Papers overview

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2017
2017
Ethanol extract of the seed of Zizyphus jujuba var. spinosa potentiates hippocampal synaptic transmission through mitogen-activated protein kinase, adenylyl cyclase, and protein kinase A pathways.
2013
2013
Kainate-induced calcium overload of cortical neurons in vitro: Dependence on expression of AMPAR GluA2-subunit and down-regulation by subnanomolar ouabain.
2013
2013
[IEM-1460 and spermine potentiate analgesic effect of fentanyl and dipyrone in rats].
  • Serdiuk SeGmiro Ve
  • Rossiiskii fiziologicheskii zhurnal imeni I.M…
  • 2013
  • Corpus ID: 23760671
Intramuscular (i. m.) administration in the minimum effective dose (MED) of central analgesics of fentanyl and dipyrone… 
2011
2011
Mechanisms of heterogeneity of calcium response to kainate and neuronal types in rat cortical primary culture
The dynamics of intracellular Ca2+ signal in response to NMDA (N-methyl-D-aspartate, 30 μM) or KA (kainite, 30 μM), its… 
2007
2007
Selective blockade of Ca2+ permeable AMPA receptors in CA1 area of rat hippocampus
2007
2007
Light triggers expression of philanthotoxin‐insensitive Ca2+‐permeable AMPA receptors in the developing rat retina
Ca2+‐permeable AMPA receptors (AMPARs) are expressed throughout the adult CNS but yet their role in development is poorly… 
2007
2007
Effect of IEM 1460 – a selective antagonist of GluR2-lacking AMPA receptors – on the action of conventional antiepileptic drugs against maximal electroshock in mice
The objective of the study was to determine the effect of combined treatment with IEM-1460 (a selective GluR2lacking, Ca2… 
2001
2001
Pharmacological Analysis of the Subunit Composition of the AMPA Receptor in Hippocampal Neurons
Experiments were performed on isolated neurons from hippocampal field CA1 and the dentate fascia to identify the subunit… 
2000
2000
Voltage‐dependent block of native AMPA receptor channels by dicationic compounds
The kinetics of open channel block of GluR2‐containing and GluR2‐lacking AMPA receptors (AMPAR) by dicationic compounds (IEM‐1460… 
1997
1997
Channel blocking drugs as tools to study glutamate receptors in insect muscles and molluscan neurons
The action of three dicationic drugs, derivatives of adamantane (IEM-1460 and IEM-1754) and phencyclidine (IEM-1925), on… 
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