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ICT2706

National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
Abstract 2224: Re-engineering of the duocarmycin structural architecture enables tumour-selective CYP2W1-mediated drug activation in human colon cancer xenografts.
There is now growing evidence that CYP1A1, 1B1, 2J2, 2S1 and 2W1 are over-expressed in many human tumour types. The ultrapotent… 
2013
2013
Cancer Therapy : Preclinical Colon Cancer – Speci fi c Cytochrome P 450 2 W 1 Converts Duocarmycin Analogues into Potent Tumor Cytotoxins
Purpose: Cytochrome P450 2W1 (CYP2W1) is a monooxygenase detected in 30% of colon cancers, whereas its expression in… 
2013
2013
Duocarmycin Analogues into Potent Tumor Cytotoxins Specific Cytochrome P 450 2 W 1 Converts − Colon Cancer
Purpose: Cytochrome P450 2W1 (CYP2W1) is a monooxygenase detected in 30% of colon cancers, whereas its expression in… 
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