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ICI 128436
Known as:
ICI 128,436
, ICI-128436
National Institutes of Health
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Related topics
Related topics
1 relation
Broader (1)
ponalrestat
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
1995
1995
Increased transendothelial permeation of albumin by high glucose concentration.
T. Yamashita
,
K. Mimura
,
F. Umeda
,
K. Kobayashi
,
T. Hashimoto
,
H. Nawata
Metabolism: clinical and experimental
1995
Corpus ID: 8271804
1993
1993
High glucose reduces specific binding for D-alpha-tocopherol in cultured aortic endothelial cells.
M. Kunisaki
,
F. Umeda
,
T. Yamauchi
,
M. Masakado
,
H. Nawata
Diabetes
1993
Corpus ID: 38087035
We investigated the effects of glucose on specific D-alpha-tocopherol binding to cultured bovine aortic endothelial cells. Our…
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1992
1992
Effect of glucose on Na, K-ATPase activity in cultured bovine aortic endothelial cells.
T. Yamashita
,
F. Umeda
,
+5 authors
H. Nawata
Endocrinologia japonica
1992
Corpus ID: 20323545
The effect of high concentrations of glucose on Na, K-ATPase activity and the polyol pathway was studied using cultured bovine…
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Highly Cited
1991
Highly Cited
1991
Clinical and Neurophysiological Studies of Aldose Reductase Inhibitor Ponalrestat in Chronic Symptomatic Diabetic Peripheral Neuropathy
C. Florkowski
,
B. Rowe
,
S. Nightingale
,
T. Harvey
,
A. Barnett
Diabetes
1991
Corpus ID: 19128280
Increased flux through the polyol pathway mediated by the enzyme aldose reductase may be associated with the development of…
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1988
1988
Effect of Statil (ICI 128436) on Erythrocyte Viscosity In Vitro
E. Rillaerts
,
J. Vertommen
,
I. D. De Leeuw
Diabetes
1988
Corpus ID: 36941688
The hypothesis that sorbitol accumulation could contribute to a reduced erythrocyte deformability in diabetes was investigated…
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1987
1987
Does Galactose Feeding Provide a Valid Model of Consequences of Exaggerated Polyol-Pathway Flux in Peripheral Nerve in Experimental Diabetes?
G. Willars
,
J. Lambourne
,
D. Tomlinson
Diabetes
1987
Corpus ID: 36617629
This study was designed to examine the effect of exaggerated polyol-pathway flux on sciatic nerve content of polyols, myo…
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Highly Cited
1986
Highly Cited
1986
Edema and increased endoneurial sodium in galactose neuropathy Reversal with an aldose reductase inhibitor
A. Mizisin
,
H. Powell
,
R. Myers
Journal of the Neurological Sciences
1986
Corpus ID: 12450215
1986
1986
Slow Component-a of Axonal Transport, Nerve myo-Inositol, and Aldose Reductase Inhibition in Streptozocin-Diabetic Rats
D. Tomlinson
,
P. Sidenius
,
Jørn Rolighed Larsen
Diabetes
1986
Corpus ID: 149033
This study measured sugars and polyols, weight/unit length, and slow component-a of axonal transport (SCa) in dorsal root…
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Highly Cited
1985
Highly Cited
1985
Properties of ICI 128,436, a novel aldose reductase inhibitor, and its effects on diabetic complications in the rat.
D. Stribling
,
D. J. Mirrlees
,
H. Harrison
,
D. C. Earl
Metabolism: clinical and experimental
1985
Corpus ID: 23265957
1985
1985
Prevention of Defective Axonal Transport in Streptozocin-diabetic Rats by Treatment with “Statil” (ICI 128436), an Aldose Reductase Inhibitor
D. Tomlinson
,
J. Townsend
,
P. Fretten
Diabetes
1985
Corpus ID: 45450734
This investigation examined the effect of treatment of streptozocin-diabetic rats with the aldose reductase inhibitor “Statil…
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