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ICI 118551

Known as: ICI 118,551, ICI-118551 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (2)

Adrenergic beta-AntagonistsPropanolamines

Narrower (1)

ICI 111,581

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2003
2003
Cardiostimulant and cardiodepressant effects through overexpressed human β2-adrenoceptors in murine heart: regional differences and functional role of β1-adrenoceptors
Abstract.(−)-Isoprenaline enhances cardiac contractility through β-adrenoceptors. However, in cardiac tissue from transgenic mice… 
2002
2002
Specific beta(2)AR blocker ICI 118,551 actively decreases contraction through a G(i)-coupled form of the beta(2)AR in myocytes from failing human heart.
BACKGROUND We have observed direct (noncatecholamine-blocking) negative inotropic effects of the selective beta(2)-adrenoceptor… 
Highly Cited
1998
Highly Cited
1998
Salmeterol inhibition of mediator release from human lung mast cells by β‐adrenoceptor‐dependent and independent mechanisms
1 The long‐acting β2‐adrenoceptor agonist, salmeterol (10−9–10−5 M), inhibited the IgE‐mediated release of histamine from human… 
Highly Cited
1995
Highly Cited
1995
Distribution and development of β‐adrenergic receptors in the rat olfactory bulb
  • C. WooM. Leon
  • The Journal of comparative neurology
  • 1995
  • Corpus ID: 23340569
Beta‐adrenergic stimulation appears to be involved in the establishment of both learned olfactory preferences and functional… 
Highly Cited
1994
Highly Cited
1994
Long-term exposure to norepinephrine results in down-regulation and reduced mRNA expression of pulmonary beta-adrenergic receptors in guinea pigs.
We studied the down-regulation of beta 2-adrenoceptors in guinea pig lung after chronic exposure to a beta-agonist. Guinea pigs… 
1989
1989
Effects of the beta 2-adrenoceptor agonist clenbuterol on tyrosine and tryptophan in plasma and brain of the rat.
The beta 2-adrenoceptor agonist, clenbuterol (initially 5 mg/kg), was found to significantly reduce plasma tyrosine and raise… 
Highly Cited
1987
Highly Cited
1987
β2-Adrenoceptor-mediated positive inotropic effect of adrenaline in human ventricular myocardium
SummaryExperiments were designed to unravel the relative contribution of β1- and β2-adrenoceptors to the positive inotropic… 
Highly Cited
1985
Highly Cited
1985
The affinity of (−)-propranolol for β1- and β1-autoreceptors of human heart
SummaryAn appraisal of the affinity of (−)-propranolol was made for β-adrenoceptors of isolated heart preparations and myocardial… 
1984
1984
Local Modulation of Noradrenaline Release In Vivo: Presynaptic β2‐Adrenoceptors and Endogenous Adrenaline
Isoprenaline bitartrate (0.5 μg/kg/min i.v.) increased the rate of noradrenaline release into the circulation of pentobarbitone… 
1983
1983
Noradrenergic regulation of growth hormone secretion in the baboon.
We have investigated the effects of iv administered noradrenergic agonists and antagonists on plasma GH concentration in the… 
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