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ICAM3 protein, human

Known as: Intercellular Adhesion Molecule 3, CD50 Antigen, ICAM-R protein, human 
Intercellular adhesion molecule 3 (547 aa, ~60 kDa) is encoded by the human ICAM3 gene. This protein plays a role in both leukocyte adhesion and… 
National Institutes of Health

Related topics

Related topics

17 relations

Broader (3)

CD AntigensCell Adhesion MoleculesLymphocyte antigen CD50
Cell AdhesionClusters of differentiationDendritic CellsEndothelial Cells

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2005
Highly Cited
2005
Specific ICAM‐3 grabbing nonintegrin‐related 1 (SIGNR1) expressed by marginal zone macrophages is essential for defense against pulmonary Streptococcus pneumoniae infection
The dendritic cell‐specific ICAM‐3‐grabbing nonintegrin (DC‐SIGN) homolog, SIGN‐related 1 (SIGNR1) is a pathogen receptor… 
Highly Cited
2002
Highly Cited
2002
Role of ICAM-3 in the initial interaction of T lymphocytes and APCs
Antigen-independent adhesive interactions between T lymphocytes and antigen-presenting cells (APCs) are essential for scanning… 
Highly Cited
1999
Highly Cited
1999
Involvement of phosphatidylinositol 3-kinase in stromal cell-derived factor-1 alpha-induced lymphocyte polarization and chemotaxis.
The role of phosphatidylinositol 3-kinase (PI3-kinase), an important enzyme involved in signal transduction events, has been… 
Highly Cited
1996
Highly Cited
1996
Distribution of immunoglobulin superfamily members ICAM-1, -2, -3, and the beta 2 integrin LFA-1 in multiple sclerosis lesions.
To identify potential molecular substrates for leukocyte trafficking and activation in multiple sclerosis (MS) brain, we… 
Highly Cited
1995
Highly Cited
1995
Crystal structure of an integrin-binding fragment of vascular cell adhesion molecule-1 at 1.8 Å resolution
THE cell-surface glycoprotein vascular cell adhesion molecule-1 (VCAM-1; ref. 1) mediates intercellular adhesion2 by specific… 
Highly Cited
1995
Highly Cited
1995
The increased expression of adhesion molecules ICAM‐3, E‐ and P‐selectins on breast cancer endothelium
Sequential interaction of neoplastic cells with the endothelium of tumour neovasculature is believed to be a significant step in… 
Highly Cited
1994
Highly Cited
1994
Characterization of the function of intercellular adhesion molecule (ICAM)-3 and comparison with ICAM-1 and ICAM-2 in immune responses
We have characterized the immunobiology of the interaction of intercellular adhesion molecule 3 (ICAM-3; CD50) with its counter… 
Highly Cited
1994
Highly Cited
1994
Involvement of the "I" domain of LFA-1 in selective binding to ligands ICAM-1 and ICAM-3
To analyze the binding requirements of LFA-1 for its two most homologous ligands, ICAM-1 and ICAM-3, we compared the effects of… 
Highly Cited
1992
Highly Cited
1992
Molecular cloning of ICAM-3, a third ligand for LFA-1, constitutively expressed on resting leukocytes
THE co-ordinated function of effector and accessory cells in the immune system is assisted by adhesion molecules on the cell… 
Highly Cited
1992
Highly Cited
1992
Intercellular adhesion molecule 3, a third adhesion counter-receptor for lymphocyte function-associated molecule 1 on resting lymphocytes
Recent studies suggest that some T and B lymphocyte cell lines bind to the integrin lymphocyte function-associated molecule 1… 
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