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Hypoxia-Responsive Elements

DNA sequences in a gene's promoter region that mediate expression during hypoxia. Since unlike normal tissues, solid tumors frequently have regions… 
National Institutes of Health

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Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
Cloning and characterization of hypoxia-inducible factor-1 subunits from Ascaris suum - a parasitic nematode highly adapted to changes of oxygen conditions during its life cycle.
2013
2013
Int6/eIF3e silenced HIF2α stabilization enhances migration and tube formation of HUVECs via IL-6 and IL-8 signaling.
2009
2009
Construction of Mutant TKGFP for Real-Time Imaging of Temporal Dynamics of HIF-1 Signal Transduction Activity Mediated by Hypoxia and Reoxygenation in Tumors in Living Mice
The herpes simplex virus type 1 thymidine kinase (HSV1-tk)/green fluorescent protein (TKGFP) dual-reporter gene and a… 
2009
2009
bFGF expression mediated by a hypoxia-regulated adenoviral vector protects PC12 cell death induced by serum deprivation.
2006
2006
Tissue-specific expression of a bHLH-PAS protein homologous to ARNT during the development of crustacean Daphnia magna.
2005
2005
Hypoxia-responsive element-mediated soluble Tie2 vector exhibits an anti-angiogenic activity in vitro under hypoxic condition.
Hypoxia-inducible factor-1 (HIF-1) is one of the key mammalian transcription factors and shows increased levels in both protein… 
2004
2004
Influences of the p53 status on hypoxia-induced gene expression.
The p53 tumor-suppressor gene is one of the most frequently mutated genes in human cancers, and its genetic alterations may play… 
Highly Cited
2001
Highly Cited
2001
A hypoxia-regulated adeno-associated virus vector for cancer-specific gene therapy.
The presence of hypoxic cells in human brain tumors is an important factor leading to resistance to radiation therapy. However… 
Highly Cited
1998
Highly Cited
1998
Enhancement of gene expression under hypoxic conditions using fragments of the human vascular endothelial growth factor and the erythropoietin genes.
1997
1997
Hypoxia stimulates atrial natriuretic peptide gene expression in cultured atrial cardiocytes.
The current study tested the hypothesis that hypoxia stimulates atrial natriuretic peptide (ANP) gene expression and secretion in… 
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