Hypoparathyroidism familial isolated
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The worldwide increases in both environmental damage and human population pressure have the unfortunate consequence that global… Expand MicroRNAs (miRNA) are endogenously expressed noncoding RNAs with important biological and pathological functions that are yet to… Expand The hypoxia-inducible factor (HIF) family of transcription factors is responsible for coordinating the cellular response to low… Expand This article outlines the need for a homeostatic response to alterations in cellular oxygenation. It describes work on… Expand The stability and transcriptional activity of the hypoxia-inducible factors (HIFs) are regulated by two oxygen-dependent events… Expand In humans both the levels and activity of the α-subunit of the hypoxia-inducible transcription factor (HIF-α) are regulated by… Expand The activity and levels of the metazoan HIF (hypoxia-inducible factor) are regulated by its hydroxylation, catalysed by 2OG (2… Expand The function of the hypoxia-inducible factor-1 (HIF-1), the key transcription factor involved in cellular adaptation to hypoxia… Expand Hypoxia-inducible factor (HIF) is a master transcriptional regulator of hypoxia-inducible genes and consists of a labile alpha… Expand The activity of the transcription factor hypoxia-inducible factor (HIF) is regulated by oxygen-dependent hydroxylation. Under… Expand