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Hypogonadotropic hypogonadism

Known as: Hypogonadism, Hypogonadotropic, Pituitary gonadotropin deficiency, Hypogonadotrophic hypogonadism 
Abnormal ovarian or testicular function due to insufficient hormonal stimulation from the hypothalamic-pituitary axis.(NICHD)
National Institutes of Health

Papers overview

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Review
2018
Review
2018
Although first identified over 70 years ago, Klinefelter syndrome (KS) continues to pose substantial diagnostic challenges, as… Expand
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Highly Cited
2012
Highly Cited
2012
Gonadotropin-releasing hormone (GnRH) is the central regulator of gonadotropins, which stimulate gonadal function. Hypothalamic… Expand
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Highly Cited
2009
Highly Cited
2009
The timely secretion of gonadal sex steroids is essential for the initiation of puberty, the postpubertal maintenance of… Expand
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Review
2008
Review
2008
GH and IGF-I are important regulators of bone homeostasis and are central to the achievement of normal longitudinal bone growth… Expand
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Highly Cited
2007
Highly Cited
2007
The G protein-coupled receptor GPR54 (AXOR12, OT7T175) is central to acquisition of reproductive competency in mammals. Peptide… Expand
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Highly Cited
2007
Highly Cited
2007
The G protein-coupled receptor Gpr54 and its ligand metastin (derived from the Kiss1 gene product kisspeptin) are key gatekeepers… Expand
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Highly Cited
2001
Highly Cited
2001
Summary Background Four retrospective studies have reported premature mortality in patients with hypopituitarism with standard… Expand
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Highly Cited
1997
Highly Cited
1997
Human obesity has an inherited component, but in contrast to rodent obesity, precise genetic defects have yet to be defined1. A… Expand
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Highly Cited
1997
Highly Cited
1997
Cross-sectional studies have demonstrated a decline in testosterone and free and bioavailable testosterone with age. This occurs… Expand
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Highly Cited
1995
Highly Cited
1995
The aromatase enzyme complex catalyzes the conversion of androgens to estrogens in a wide variety of tissues, including the ovary… Expand
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