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Hymecromone

Known as: Methylumbelliferone, 2H-1-Benzopyran-2-one, 7-hydroxy-4-methyl-, 4-Methylumbelliferone 
A coumarin derivative possessing properties as a spasmolytic, choleretic and light-protective agent. It is also used in ANALYTICAL CHEMISTRY… 
National Institutes of Health

Related topics

Related topics

41 relations

Narrower (33)

3-chloro-4-methylumbelliferone4-methylumbelliferyl beta-D-ribopyranoside4-methylumbelliferyl butyrate4-methylumbelliferyl caprylate
In Bloodagonistsanalogs & derivativesantagonists & inhibitors

Broader (1)

Indicators and Reagents

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2007
Highly Cited
2007
Critical Roles of Residues 36 and 40 in the Phenol and Tertiary Amine Aglycone Substrate Selectivities of UDP-Glucuronosyltransferases 1A3 and 1A4
Despite high sequence identity, UGT1A3 and UGT1A4 differ in terms of substrate selectivity. UGT1A3 glucuronidates the planar… 
Highly Cited
2006
Highly Cited
2006
The Important Role of Bcrp (Abcg2) in the Biliary Excretion of Sulfate and Glucuronide Metabolites of Acetaminophen, 4-Methylumbelliferone, and Harmol in Mice
The role of Mrp2, Bcrp, and P-glycoprotein in the biliary excretion of acetaminophen sulfate (AS) and glucuronide (AG), 4… 
Highly Cited
2006
Highly Cited
2006
Differential Involvement of Mrp2 (Abcc2) and Bcrp (Abcg2) in Biliary Excretion of 4-Methylumbelliferyl Glucuronide and Sulfate in the Rat
The hepatic excretion of hydrophilic conjugates, end products of phase II metabolism, is not completely understood. In the… 
Highly Cited
1993
Highly Cited
1993
Extracorporeal Application of a Gel-Entrapment, Bioartificial Liver: Demonstration of Drug Metabolism and Other Biochemical Functions
Metabolic activity of a gel-entrapment, hollow fiber, bioartificial liver was evaluated in vitro and during extracorporeal… 
Highly Cited
1987
Highly Cited
1987
Characterization and tissue specificity of a monoclonal antibody against human uridine 5'-diphosphate-glucuronosyltransferase.
Highly Cited
1980
Highly Cited
1980
Determination of acid hydrolases in human platelets.
Highly Cited
1978
Highly Cited
1978
Metabolism of benzo(a)pyrene-3,6-quinone and 3-hydroxybenzo(a)pyrene in liver microsomes from 3-methylcholanthrene-treated rats. A possible role of DT-diaphorase in the formation of glucuronyl…
Highly Cited
1977
Highly Cited
1977
Genetic regulation of UDP-glucuronosyltransferase induction by polycyclic aromatic compounds in mice. Co-segregation with aryl hydrocarbon (benzo(alpha)pyrene) hydroxylase induction.
Highly Cited
1977
Highly Cited
1977
Rapid biochemical tests for characterization of the Mycoplasmatales
Methods are described for the rapid detection of beta-D-glucosidase and phosphatase in mycoplasma cultures using fluorogenic 4… 
Highly Cited
1967
Highly Cited
1967
Fluorometric assay for the hydrolytic activity of lipase using fatty acyl esters of 4-methylumbelliferone.
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