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Hycanthone

Known as: 9H-Thioxanthen-9-one, 1-((2-(diethylamino)ethyl)amino)-4-(hydroxymethyl)-, HYC, Hycanthone [Chemical/Ingredient] 
A thioxanthene derivative of lucanthone with anti-schistosomal activity and potential antineoplastic activity. Hycanthone interferes with parasite… 
National Institutes of Health

Related topics

Related topics

12 relations

Narrower (3)

EtrenolIA 4hycanthone methanesulfonate
In BloodNCIt Antineoplastic Agent Terminologyagonistsanalogs & derivatives

Broader (1)

Schistosomicides

Papers overview

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Review
1987
Review
1987
Evaluation of potential mammalian genotoxins using Drosophila: the need for a change in test strategy.
Recent developments in the field of genetic toxicology testing, in particular the outcome of several international collaborative… 
1980
1980
In vitro information system for collection and analysis of experimental data.
The In Vitro information System (IVIS) provides for the collection, maintenance, analysis and reporting of mutagenesis data for… 
1977
1977
Effects of hycanthone on neuromuscular systems of Schistoma mansoni.
Hycanthone has a variety of effects on muscular activity and neurotransmitter systems of schistosomes. These include interference… 
1975
1975
A comparative study on the genetic effects of hycanthone and oxamniquine.
Oxamniquine (UK-4271; 6-hydroxymethyl-2-isopropylaminomethyl-7-nitro-1,2,3,4-tetrahydroquinoline) is a new schistosomicidal agent… 
1975
1975
Results of tests for possible transmitted genetic effects of hycanthone in mammals.
Extensive tests to detect transmitted genetic effects of hycanthone in mammals have been made to provide the most pertinent… 
1974
1974
Teratogenic and cytogenetic effects of hycanthone in mice and rabbits.
Hycanthone administered daily to pregnant mice at 3 dose levels on days 61–11 of gestation produced embryolethality and a… 
1971
1971
Clinical trial of hycanthone in Schistosomiasis mansoni in St. Lucia.
A clinical trial of a new antischistosomal drug, hycanthone methanesulfonate, was undertaken in 103 patients with schistosomiasis… 
1970
1970
The uptake of tritiated hycanthone by male and female Schistosoma mansoni worms and distribution of the drug in plasma and whole blood of mice following a single intramuscular injection.
Mice infected with Schistosoma mansoni were given an intramuscular injection of a single 80 mg/kg dose of randomly tritiated… 
1968
1968
Preliminary clinical trials with hycanthone, a new antischistosomal agent.
Summary From Miracil D® (lucanthone), a hydroxymethyl derivative (hycanthone), can be obtained through the biological activity of… 
1966
1966
Transition-metal Chelates of Hydrazincarboxylic Acid
  • Antonio BraibantiG. BigliardiA. M. Manotti LanfrediAntonio Tiripicchio
  • Nature
  • 1966
  • Corpus ID: 4184288
THE structural and chemical properties of compounds formed by hydrazincarboxylic acid, H2N′-NH.COOH, with transition metals are…