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Hycanthone

Known as: 9H-Thioxanthen-9-one, 1-((2-(diethylamino)ethyl)amino)-4-(hydroxymethyl)-, HYC, Hycanthone [Chemical/Ingredient] 
A thioxanthene derivative of lucanthone with anti-schistosomal activity and potential antineoplastic activity. Hycanthone interferes with parasite… Expand
National Institutes of Health

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Highly Cited
2014
Highly Cited
2014
The salience network (SN) serves to identify salient stimuli and to switch between the central executive network (CEN) and the… Expand
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Highly Cited
2011
Highly Cited
2011
  • Y. Wang, L. Zhao, +8 authors S. Chen
  • Proceedings of the National Academy of Sciences
  • 2011
  • Corpus ID: 23170430
The full-length AML1-ETO (AE) fusion gene resulting from t(8;21)(q22;q22) in human acute myeloid leukemia (AML) is not sufficient… Expand
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Highly Cited
2008
Highly Cited
2008
Abstract Introduction: Low dietary intake of docosahexaenoic acid (DHA) and/or foods rich in lutein may be associated with… Expand
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Highly Cited
2006
Highly Cited
2006
BackgroundIn Escherichia coli, pH regulates genes for amino-acid and sugar catabolism, electron transport, oxidative stress… Expand
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Highly Cited
2004
Highly Cited
2004
We have determined the entire DNA sequence of pLVPK, which is a 219-kb virulence plasmid harbored in a bacteremic isolate of… Expand
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Highly Cited
1997
Highly Cited
1997
Anaerobic, but not aerobic, cultures of Escherichia coli accumulated Tc(VII) and reduced it to a black insoluble precipitate. Tc… Expand
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Highly Cited
1986
Highly Cited
1986
Mice were treated with potassium antimony tartrate, hycanthone, oxamniquine, niridazole, or praziquantel at different times after… Expand
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Highly Cited
1972
Highly Cited
1972
Several carcinogenic metabolites of the carcinogen 2-acetyl-aminofluorene, especially 2-nitrosofluorene and N-hydroxy-2… Expand
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Highly Cited
1971
Highly Cited
1971
Rapid spot-test screening of antischistosomal agents reveals that hycanthone is a potent frameshift mutagen while the closely… Expand
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Highly Cited
1970
Highly Cited
1970
  • M. Waring
  • Journal of molecular biology
  • 1970
  • Corpus ID: 37380594
Abstract Intercalation models for the binding of drugs to DNA involve the postulate of drug-induced local uncoiling of the double… Expand
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